Maternal Immunity and Vaccination Influence Disease Severity in Progeny in a Novel Mast Cell-Deficient Mouse Model of Severe Dengue

Sub-neutralizing concentrations of antibodies in dengue infected patients is a major risk factor for the development of dengue hemorrhagic fever and dengue shock syndrome. Here, we describe a mouse model with a deficiency in mast cells (MCs) in addition to a deficiency in Type-I and II IFN receptors...

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Detalles Bibliográficos
Autores principales: Mantri, Chinmay Kumar, Soundarajan, Gayathri, Saron, Wilfried A. A., Rathore, Abhay P. S., Alonso, Sylvie, St. John, Ashley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152039/
https://www.ncbi.nlm.nih.gov/pubmed/34066286
http://dx.doi.org/10.3390/v13050900

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