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Long-Term Effectiveness of Treating Dentin Hypersensitivity with Bifluorid 10 and Futurabond U: A Split-Mouth Randomized Double-Blind Clinical Trial

Background: The definition of dental hypersensitivity is “pain derived from exposed dentin in response to chemical, thermal tactile or osmotic stimuli which cannot be explained as arising from any other dental defect or disease”. One of the treatments proposed is tubular occlusion. The aim of this i...

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Autores principales: Mazur, Marta, Jedliński, Maciej, Ndokaj, Artnora, Ardan, Roman, Janiszewska-Olszowska, Joanna, Nardi, Gianna Maria, Ottolenghi, Livia, Guerra, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152040/
https://www.ncbi.nlm.nih.gov/pubmed/34066300
http://dx.doi.org/10.3390/jcm10102085
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author Mazur, Marta
Jedliński, Maciej
Ndokaj, Artnora
Ardan, Roman
Janiszewska-Olszowska, Joanna
Nardi, Gianna Maria
Ottolenghi, Livia
Guerra, Fabrizio
author_facet Mazur, Marta
Jedliński, Maciej
Ndokaj, Artnora
Ardan, Roman
Janiszewska-Olszowska, Joanna
Nardi, Gianna Maria
Ottolenghi, Livia
Guerra, Fabrizio
author_sort Mazur, Marta
collection PubMed
description Background: The definition of dental hypersensitivity is “pain derived from exposed dentin in response to chemical, thermal tactile or osmotic stimuli which cannot be explained as arising from any other dental defect or disease”. One of the treatments proposed is tubular occlusion. The aim of this in vivo split-mouth randomized clinical trial was to evaluate the clinical efficacy of a in-office application of a fluoride varnish (Bifluorid 10) and a bonding resin (Futurabond U) in adults with dentin hypersensitivity. Material and methods: A total of 180 teeth were treated with Bifluorid 10 and 160 with Futurabond U. Outcome measurements were taken one or two weeks before treatment, at baseline at the application days, at 1 week and at 1–6 months after first treatment. Results: Both treatments reduced pain intensity. Bifluorid 10 and Futurabond U have similar efficacy in reducing SCHIFF-measured pain reduction, while Bifluorid 10 is significantly more efficient for VAS-measured pain reduction, mainly due to long-term pain reduction. Patient age has a significant negative influence on pain reduction, while the influence of patient gender and BEWE of the tooth is insignificant. Conclusions: Bifluorid 10 and Futurabond U are effective in the treatment of dental hypersensitivity. The RCT was registered at the US National Institutes of Health (ClinicalTrials.gov) #NCT04813848.
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spelling pubmed-81520402021-05-27 Long-Term Effectiveness of Treating Dentin Hypersensitivity with Bifluorid 10 and Futurabond U: A Split-Mouth Randomized Double-Blind Clinical Trial Mazur, Marta Jedliński, Maciej Ndokaj, Artnora Ardan, Roman Janiszewska-Olszowska, Joanna Nardi, Gianna Maria Ottolenghi, Livia Guerra, Fabrizio J Clin Med Article Background: The definition of dental hypersensitivity is “pain derived from exposed dentin in response to chemical, thermal tactile or osmotic stimuli which cannot be explained as arising from any other dental defect or disease”. One of the treatments proposed is tubular occlusion. The aim of this in vivo split-mouth randomized clinical trial was to evaluate the clinical efficacy of a in-office application of a fluoride varnish (Bifluorid 10) and a bonding resin (Futurabond U) in adults with dentin hypersensitivity. Material and methods: A total of 180 teeth were treated with Bifluorid 10 and 160 with Futurabond U. Outcome measurements were taken one or two weeks before treatment, at baseline at the application days, at 1 week and at 1–6 months after first treatment. Results: Both treatments reduced pain intensity. Bifluorid 10 and Futurabond U have similar efficacy in reducing SCHIFF-measured pain reduction, while Bifluorid 10 is significantly more efficient for VAS-measured pain reduction, mainly due to long-term pain reduction. Patient age has a significant negative influence on pain reduction, while the influence of patient gender and BEWE of the tooth is insignificant. Conclusions: Bifluorid 10 and Futurabond U are effective in the treatment of dental hypersensitivity. The RCT was registered at the US National Institutes of Health (ClinicalTrials.gov) #NCT04813848. MDPI 2021-05-12 /pmc/articles/PMC8152040/ /pubmed/34066300 http://dx.doi.org/10.3390/jcm10102085 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mazur, Marta
Jedliński, Maciej
Ndokaj, Artnora
Ardan, Roman
Janiszewska-Olszowska, Joanna
Nardi, Gianna Maria
Ottolenghi, Livia
Guerra, Fabrizio
Long-Term Effectiveness of Treating Dentin Hypersensitivity with Bifluorid 10 and Futurabond U: A Split-Mouth Randomized Double-Blind Clinical Trial
title Long-Term Effectiveness of Treating Dentin Hypersensitivity with Bifluorid 10 and Futurabond U: A Split-Mouth Randomized Double-Blind Clinical Trial
title_full Long-Term Effectiveness of Treating Dentin Hypersensitivity with Bifluorid 10 and Futurabond U: A Split-Mouth Randomized Double-Blind Clinical Trial
title_fullStr Long-Term Effectiveness of Treating Dentin Hypersensitivity with Bifluorid 10 and Futurabond U: A Split-Mouth Randomized Double-Blind Clinical Trial
title_full_unstemmed Long-Term Effectiveness of Treating Dentin Hypersensitivity with Bifluorid 10 and Futurabond U: A Split-Mouth Randomized Double-Blind Clinical Trial
title_short Long-Term Effectiveness of Treating Dentin Hypersensitivity with Bifluorid 10 and Futurabond U: A Split-Mouth Randomized Double-Blind Clinical Trial
title_sort long-term effectiveness of treating dentin hypersensitivity with bifluorid 10 and futurabond u: a split-mouth randomized double-blind clinical trial
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152040/
https://www.ncbi.nlm.nih.gov/pubmed/34066300
http://dx.doi.org/10.3390/jcm10102085
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