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Does COVID 19 generate a milieu for propagation of mucormycosis?

Corona Virus Disease 2019 (COVID 2019), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a dreadful infectious disease which has emerged as one of the most significant medical emergency affecting everyone directly or indirectly. COVID 2019 is a multisystem disease and c...

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Autores principales: Pandiar, Deepak, Kumar, N. Siva, Anand, Rahul, Kamboj, Mala, Narwal, Anjali, Shameena, P.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152198/
https://www.ncbi.nlm.nih.gov/pubmed/34087613
http://dx.doi.org/10.1016/j.mehy.2021.110613
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author Pandiar, Deepak
Kumar, N. Siva
Anand, Rahul
Kamboj, Mala
Narwal, Anjali
Shameena, P.M.
author_facet Pandiar, Deepak
Kumar, N. Siva
Anand, Rahul
Kamboj, Mala
Narwal, Anjali
Shameena, P.M.
author_sort Pandiar, Deepak
collection PubMed
description Corona Virus Disease 2019 (COVID 2019), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a dreadful infectious disease which has emerged as one of the most significant medical emergency affecting everyone directly or indirectly. COVID 2019 is a multisystem disease and causes severe immunosuppression. Initially thought to affect mainly the respiratory system, it strikes all vital organ systems and cause defects in cardio-circulatory, respiratory system and gastrointestinal systems to name a few leading to copious biochemical alterations. Reports show there is thromoembolism, raised ferritin levels, lymphocytopenia, thrombocytopenia, lactic acidosis, acute diabetes like state and cytokine storm. Data regarding levels of neutrophils is equivocal. Further there is increased incidence regarding high incidents of mucormycosis in COVID 2019 positive subjects. In the present paper, we identified and correlated the virus mediated biochemical alterations as the potential ideal environment for propagation of mucorales; and thus concentrate on early diagnosis and treatment of mucormycosis in COVID 2019 cases.
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spelling pubmed-81521982021-05-28 Does COVID 19 generate a milieu for propagation of mucormycosis? Pandiar, Deepak Kumar, N. Siva Anand, Rahul Kamboj, Mala Narwal, Anjali Shameena, P.M. Med Hypotheses Article Corona Virus Disease 2019 (COVID 2019), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a dreadful infectious disease which has emerged as one of the most significant medical emergency affecting everyone directly or indirectly. COVID 2019 is a multisystem disease and causes severe immunosuppression. Initially thought to affect mainly the respiratory system, it strikes all vital organ systems and cause defects in cardio-circulatory, respiratory system and gastrointestinal systems to name a few leading to copious biochemical alterations. Reports show there is thromoembolism, raised ferritin levels, lymphocytopenia, thrombocytopenia, lactic acidosis, acute diabetes like state and cytokine storm. Data regarding levels of neutrophils is equivocal. Further there is increased incidence regarding high incidents of mucormycosis in COVID 2019 positive subjects. In the present paper, we identified and correlated the virus mediated biochemical alterations as the potential ideal environment for propagation of mucorales; and thus concentrate on early diagnosis and treatment of mucormycosis in COVID 2019 cases. Elsevier Ltd. 2021-07 2021-05-26 /pmc/articles/PMC8152198/ /pubmed/34087613 http://dx.doi.org/10.1016/j.mehy.2021.110613 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Pandiar, Deepak
Kumar, N. Siva
Anand, Rahul
Kamboj, Mala
Narwal, Anjali
Shameena, P.M.
Does COVID 19 generate a milieu for propagation of mucormycosis?
title Does COVID 19 generate a milieu for propagation of mucormycosis?
title_full Does COVID 19 generate a milieu for propagation of mucormycosis?
title_fullStr Does COVID 19 generate a milieu for propagation of mucormycosis?
title_full_unstemmed Does COVID 19 generate a milieu for propagation of mucormycosis?
title_short Does COVID 19 generate a milieu for propagation of mucormycosis?
title_sort does covid 19 generate a milieu for propagation of mucormycosis?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152198/
https://www.ncbi.nlm.nih.gov/pubmed/34087613
http://dx.doi.org/10.1016/j.mehy.2021.110613
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