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Characterization of a Novel Nanocomposite Film Based on Functionalized Chitosan–Pt–Fe(3)O(4) Hybrid Nanoparticles

The development of organic—inorganic hybrids or nanocomposite films is increasingly becoming attractive in light of their emerging applications. This research focuses on the formation of a unique nanocomposite film with enhanced elasticity suitable for many biomedical applications. The physical prop...

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Detalles Bibliográficos
Autores principales: Kumari, Sangeeta, Singh, Raj Pal, Chavan, Nayaku N., Sahi, Shivendra V., Sharma, Nilesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152257/
https://www.ncbi.nlm.nih.gov/pubmed/34067953
http://dx.doi.org/10.3390/nano11051275
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author Kumari, Sangeeta
Singh, Raj Pal
Chavan, Nayaku N.
Sahi, Shivendra V.
Sharma, Nilesh
author_facet Kumari, Sangeeta
Singh, Raj Pal
Chavan, Nayaku N.
Sahi, Shivendra V.
Sharma, Nilesh
author_sort Kumari, Sangeeta
collection PubMed
description The development of organic—inorganic hybrids or nanocomposite films is increasingly becoming attractive in light of their emerging applications. This research focuses on the formation of a unique nanocomposite film with enhanced elasticity suitable for many biomedical applications. The physical property measurement system and transmission electron microscopy were used to analyze Pt–Fe(3)O(4) hybrid nanoparticles. These nanohybrids exhibited magnetic effects. They were further exploited to prepare the nanocomposite films in conjunction with a chitosan-g–glycolic acid organic fraction. The nanocomposite films were then examined using standard techniques: thermogravimetric analysis, X-ray diffraction, Fourier transform infrared spectroscopy, and atomic force microscopy. Tensile strength testing demonstrated a significantly greater elastic strength of these nanocomposite films than pure chitosan films. The water absorption behavior of the nanocomposites was evaluated by measuring swelling degree. These nanocomposites were observed to have substantially improved physical properties. Such novel nanocomposites can be extended to various biomedical applications, which include drug delivery and tissue engineering.
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spelling pubmed-81522572021-05-27 Characterization of a Novel Nanocomposite Film Based on Functionalized Chitosan–Pt–Fe(3)O(4) Hybrid Nanoparticles Kumari, Sangeeta Singh, Raj Pal Chavan, Nayaku N. Sahi, Shivendra V. Sharma, Nilesh Nanomaterials (Basel) Article The development of organic—inorganic hybrids or nanocomposite films is increasingly becoming attractive in light of their emerging applications. This research focuses on the formation of a unique nanocomposite film with enhanced elasticity suitable for many biomedical applications. The physical property measurement system and transmission electron microscopy were used to analyze Pt–Fe(3)O(4) hybrid nanoparticles. These nanohybrids exhibited magnetic effects. They were further exploited to prepare the nanocomposite films in conjunction with a chitosan-g–glycolic acid organic fraction. The nanocomposite films were then examined using standard techniques: thermogravimetric analysis, X-ray diffraction, Fourier transform infrared spectroscopy, and atomic force microscopy. Tensile strength testing demonstrated a significantly greater elastic strength of these nanocomposite films than pure chitosan films. The water absorption behavior of the nanocomposites was evaluated by measuring swelling degree. These nanocomposites were observed to have substantially improved physical properties. Such novel nanocomposites can be extended to various biomedical applications, which include drug delivery and tissue engineering. MDPI 2021-05-13 /pmc/articles/PMC8152257/ /pubmed/34067953 http://dx.doi.org/10.3390/nano11051275 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kumari, Sangeeta
Singh, Raj Pal
Chavan, Nayaku N.
Sahi, Shivendra V.
Sharma, Nilesh
Characterization of a Novel Nanocomposite Film Based on Functionalized Chitosan–Pt–Fe(3)O(4) Hybrid Nanoparticles
title Characterization of a Novel Nanocomposite Film Based on Functionalized Chitosan–Pt–Fe(3)O(4) Hybrid Nanoparticles
title_full Characterization of a Novel Nanocomposite Film Based on Functionalized Chitosan–Pt–Fe(3)O(4) Hybrid Nanoparticles
title_fullStr Characterization of a Novel Nanocomposite Film Based on Functionalized Chitosan–Pt–Fe(3)O(4) Hybrid Nanoparticles
title_full_unstemmed Characterization of a Novel Nanocomposite Film Based on Functionalized Chitosan–Pt–Fe(3)O(4) Hybrid Nanoparticles
title_short Characterization of a Novel Nanocomposite Film Based on Functionalized Chitosan–Pt–Fe(3)O(4) Hybrid Nanoparticles
title_sort characterization of a novel nanocomposite film based on functionalized chitosan–pt–fe(3)o(4) hybrid nanoparticles
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152257/
https://www.ncbi.nlm.nih.gov/pubmed/34067953
http://dx.doi.org/10.3390/nano11051275
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