Hyoscyamus albus nortropane alkaloids reduce hyperglycemia and hyperinsulinemia induced in HepG2 cells through the regulation of SIRT1/NF-kB/JNK pathway

BACKGROUND: Chronic superphysiological glucose and insulin concentrations are known to trigger several tissue and organ failures, including insulin resistance, oxidative stress and chronic low-grade inflammation. Hence, the screening for molecules that may counteract such conditions is essential in...

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Detalles Bibliográficos
Autores principales: Kowalczuk, Anna, Bourebaba, Nabila, Kornicka-Garbowska, Katarzyna, Turlej, Eliza, Marycz, Krzysztof, Bourebaba, Lynda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152357/
https://www.ncbi.nlm.nih.gov/pubmed/34034759
http://dx.doi.org/10.1186/s12964-021-00735-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152357/
https://www.ncbi.nlm.nih.gov/pubmed/34034759
http://dx.doi.org/10.1186/s12964-021-00735-w

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