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A multifunctional nanoprobe for targeting tumors and mitochondria with singlet oxygen generation and monitoring mitochondrion pH changes in cancer cells by ratiometric fluorescence imaging

Mitochondria are the main sites of cell metabolism. Even minor pH changes may lead to mitochondrial dysfunction and promote cell apoptosis. Mitochondrion-targeting photosensitizers can produce singlet oxygen in the mitochondria. In tumor photodynamic therapy (PDT), tumor cells are killed through sin...

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Detalles Bibliográficos
Autores principales: Zhao, Jingjin, Zou, Mengbing, Huang, Mengjiao, Zhang, Liangliang, Yang, Keqin, Zhao, Shulin, Liu, Yi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152412/
https://www.ncbi.nlm.nih.gov/pubmed/34094052
http://dx.doi.org/10.1039/d0sc00757a