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A multifunctional nanoprobe for targeting tumors and mitochondria with singlet oxygen generation and monitoring mitochondrion pH changes in cancer cells by ratiometric fluorescence imaging
Mitochondria are the main sites of cell metabolism. Even minor pH changes may lead to mitochondrial dysfunction and promote cell apoptosis. Mitochondrion-targeting photosensitizers can produce singlet oxygen in the mitochondria. In tumor photodynamic therapy (PDT), tumor cells are killed through sin...
Autores principales: | Zhao, Jingjin, Zou, Mengbing, Huang, Mengjiao, Zhang, Liangliang, Yang, Keqin, Zhao, Shulin, Liu, Yi-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152412/ https://www.ncbi.nlm.nih.gov/pubmed/34094052 http://dx.doi.org/10.1039/d0sc00757a |
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