Whole exome sequencing and trio analysis to broaden the variant spectrum of genes in idiopathic hypogonadotropic hypogonadism

Dozens of genes are associated with idiopathic hypogonadotropic hypogonadism (IHH) and an oligogenic etiology has been suggested. However, the associated genes may account for only approximately 50% cases. In addition, a genomic systematic pedigree analysis is still lacking. Here, we conducted whole...

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Detalles Bibliográficos
Autores principales: Zhang, Jian, Tang, Shu-Yan, Zhu, Xiao-Bin, Li, Peng, Lu, Jian-Qi, Cong, Jiang-Shan, Wang, Ling-Bo, Zhang, Feng, Li, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152424/
https://www.ncbi.nlm.nih.gov/pubmed/33208564
http://dx.doi.org/10.4103/aja.aja_65_20

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