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Current Evidence, Challenges, and Opportunities of Physiologically Based Pharmacokinetic Models of Atorvastatin for Decision Making

Atorvastatin (ATS) is the gold-standard treatment worldwide for the management of hypercholesterolemia and prevention of cardiovascular diseases associated with dyslipidemia. Physiologically based pharmacokinetic (PBPK) models have been positioned as a valuable tool for the characterization of compl...

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Detalles Bibliográficos
Autores principales:	Reig-López, Javier, García-Arieta, Alfredo, Mangas-Sanjuán, Víctor, Merino-Sanjuán, Matilde
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152487/ https://www.ncbi.nlm.nih.gov/pubmed/34068030 http://dx.doi.org/10.3390/pharmaceutics13050709

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