Cargando…
What Is New in Helicobacter pylori Diagnosis. An Overview
Helicobacter pylori infection remains one of the most prevalent infections worldwide, especially in low-resource countries, and the major risk factor for peptic ulcer and gastric cancer. The “test-and-treat” strategy is recommended by several guidelines and consensus. The choice of testing method is...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152493/ https://www.ncbi.nlm.nih.gov/pubmed/34068062 http://dx.doi.org/10.3390/jcm10102091 |
_version_ | 1783698618749812736 |
---|---|
author | Dore, Maria Pina Pes, Giovanni Mario |
author_facet | Dore, Maria Pina Pes, Giovanni Mario |
author_sort | Dore, Maria Pina |
collection | PubMed |
description | Helicobacter pylori infection remains one of the most prevalent infections worldwide, especially in low-resource countries, and the major risk factor for peptic ulcer and gastric cancer. The “test-and-treat” strategy is recommended by several guidelines and consensus. The choice of testing method is based on patient age, presence of alarm signs and/or symptoms, use of non-steroidal anti-inflammatory drugs, as well as local availability, test reliability, and cost. Culture is the gold standard to detect H. pylori and, possibly, to perform susceptibility testing, however, it requires upper endoscopy and dedicated labs. Recent advances in molecular biology have provided new strategies in detecting infection and antimicrobial resistance without invasive tests. In this review we attempt to offer a comprehensive panorama on the new diagnostic tools and their potential use in clinical settings, in order to accomplish specific recommendations. |
format | Online Article Text |
id | pubmed-8152493 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81524932021-05-27 What Is New in Helicobacter pylori Diagnosis. An Overview Dore, Maria Pina Pes, Giovanni Mario J Clin Med Review Helicobacter pylori infection remains one of the most prevalent infections worldwide, especially in low-resource countries, and the major risk factor for peptic ulcer and gastric cancer. The “test-and-treat” strategy is recommended by several guidelines and consensus. The choice of testing method is based on patient age, presence of alarm signs and/or symptoms, use of non-steroidal anti-inflammatory drugs, as well as local availability, test reliability, and cost. Culture is the gold standard to detect H. pylori and, possibly, to perform susceptibility testing, however, it requires upper endoscopy and dedicated labs. Recent advances in molecular biology have provided new strategies in detecting infection and antimicrobial resistance without invasive tests. In this review we attempt to offer a comprehensive panorama on the new diagnostic tools and their potential use in clinical settings, in order to accomplish specific recommendations. MDPI 2021-05-13 /pmc/articles/PMC8152493/ /pubmed/34068062 http://dx.doi.org/10.3390/jcm10102091 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Dore, Maria Pina Pes, Giovanni Mario What Is New in Helicobacter pylori Diagnosis. An Overview |
title | What Is New in Helicobacter pylori Diagnosis. An Overview |
title_full | What Is New in Helicobacter pylori Diagnosis. An Overview |
title_fullStr | What Is New in Helicobacter pylori Diagnosis. An Overview |
title_full_unstemmed | What Is New in Helicobacter pylori Diagnosis. An Overview |
title_short | What Is New in Helicobacter pylori Diagnosis. An Overview |
title_sort | what is new in helicobacter pylori diagnosis. an overview |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152493/ https://www.ncbi.nlm.nih.gov/pubmed/34068062 http://dx.doi.org/10.3390/jcm10102091 |
work_keys_str_mv | AT doremariapina whatisnewinhelicobacterpyloridiagnosisanoverview AT pesgiovannimario whatisnewinhelicobacterpyloridiagnosisanoverview |