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Combined Impact of Inflammation and Pharmacogenomic Variants on Voriconazole Trough Concentrations: A Meta-Analysis of Individual Data

Few studies have simultaneously investigated the impact of inflammation and genetic polymorphisms of cytochromes P450 2C19 and 3A4 on voriconazole trough concentrations. We aimed to define the respective impact of inflammation and genetic polymorphisms on voriconazole exposure by performing individu...

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Detalles Bibliográficos
Autores principales: Bolcato, Léa, Khouri, Charles, Veringa, Anette, Alffenaar, Jan Willem C., Yamada, Takahiro, Naito, Takafumi, Lamoureux, Fabien, Fonrose, Xavier, Stanke-Labesque, Françoise, Gautier-Veyret, Elodie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152514/
https://www.ncbi.nlm.nih.gov/pubmed/34068031
http://dx.doi.org/10.3390/jcm10102089