Tandem sequential catalytic enantioselective synthesis of highly-functionalised tetrahydroindolizine derivatives

An isothiourea-catalysed enantioselective synthesis of novel tetrahydroindolizine derivatives is reported through a one-pot tandem sequential process. The application of 2-(pyrrol-1-yl)acetic acid in combination with either a trifluoromethyl enone or an α-keto-β,γ-unsaturated ester in an enantiosele...

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Detalles Bibliográficos
Autores principales: Zhang, Shuyue, Greenhalgh, Mark D., Slawin, Alexandra M. Z., Smith, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152628/
https://www.ncbi.nlm.nih.gov/pubmed/34122857
http://dx.doi.org/10.1039/d0sc00432d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152628/
https://www.ncbi.nlm.nih.gov/pubmed/34122857
http://dx.doi.org/10.1039/d0sc00432d

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