Cargando…

Transition-metal-free C(sp(3))–H/C(sp(3))–H dehydrogenative coupling of saturated heterocycles with N-benzyl imines

A unique C(sp(3))–H/C(sp(3))–H dehydrocoupling of N-benzylimines with saturated heterocycles is described. Using super electron donor (SED) 2-azaallyl anions and aryl iodides as electron acceptors, single-electron-transfer (SET) generates an aryl radical. Hydrogen atom transfer (HAT) from saturated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Zhengfen, Li, Minyan, Deng, Guogang, Wei, Wanshi, Feng, Ping, Zi, Quanxing, Li, Tiantian, Zhang, Hongbin, Yang, Xiaodong, Walsh, Patrick J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152681/ https://www.ncbi.nlm.nih.gov/pubmed/34094139 http://dx.doi.org/10.1039/d0sc00031k

Ejemplares similares

Metal-free oxidative cross-dehydrogenative coupling of quinones with benzylic C(sp(3))–H bonds
por: Dong, Yu, et al.
Publicado: (2019)

Copper-catalyzed dehydrogenative γ-C(sp(3))-H amination of saturated ketones for synthesis of polysubstituted anilines
por: Hu, Rong, et al.
Publicado: (2019)

Copper-Mediated Dehydrogenative C(sp(3))–H Borylation of Alkanes
por: Sang, Ruocheng, et al.
Publicado: (2023)

Electrochemical Dehydrogenative C(sp(2))−H Amination
por: Puthanveedu, Mahesh, et al.
Publicado: (2021)

Electrochemical Benzylic C(sp(3))–H Acyloxylation
por: Atkins, Alexander P., et al.
Publicado: (2022)

Pyridine-enabled copper-promoted cross dehydrogenative coupling of C(sp(2))–H and unactivated C(sp(3))–H bonds
por: Wu, Xuesong, et al.
Publicado: (2015)

Author Correction: Copper-catalyzed dehydrogenative γ-C(sp(3))-H amination of saturated ketones for synthesis of polysubstituted anilines
por: Hu, Rong, et al.
Publicado: (2021)

Palladium‐Catalyzed Directed C(sp(3))–H Arylation of Saturated Heterocycles at C‐3 Using a Concise Optimization Approach
por: Affron, Dominic P., et al.
Publicado: (2015)

Multicomponent double Mannich alkylamination involving C(sp(2))–H and benzylic C(sp(3))–H bonds
por: Lai, Zhencheng, et al.
Publicado: (2022)

Iodine(III) promotes cross-dehydrogenative coupling of N-hydroxyphthalimide and unactivated C(sp(3))–H bonds
por: Wu, Fufang, et al.
Publicado: (2021)

Synthesis of 2-oxindoles via 'transition-metal-free' intramolecular dehydrogenative coupling (IDC) of sp(2) C–H and sp(3) C–H bonds
por: Kumar, Nivesh, et al.
Publicado: (2016)

Electrochemical Dehydrogenative C−H Aminomethylation of Imidazopyridines and Related Heterocycles
por: Huang, Raolin, et al.
Publicado: (2022)

Temperature-modulated selective C(sp(3))–H or C(sp(2))–H arylation through palladium catalysis
por: Gogula, Thirupathi, et al.
Publicado: (2020)

Copper catalyzed late-stage C(sp(3))-H functionalization of nitrogen heterocycles
por: Chang, Zhe, et al.
Publicado: (2021)

Manganese-catalyzed benzylic C(sp(3))–H amination for late-stage functionalization
por: Clark, Joseph R., et al.
Publicado: (2018)

Ni-catalyzed benzylic β-C(sp(3))–H bond activation of formamides
por: Wang, Rong-Hua, et al.
Publicado: (2022)

Copper-catalyzed diastereoselective aerobic intramolecular dehydrogenative coupling of hydrazones via sp(3) C–H functionalization
por: Wu, Xuesong, et al.
Publicado: (2015)

Allylic C(sp(3))–H alkylation via synergistic organo- and photoredox catalyzed radical addition to imines
por: Jia, Jiaqi, et al.
Publicado: (2020)

Ligand-Promoted Alkylation of C(sp(3))–H and C(sp(2))–H Bonds
por: Zhu, Ru-Yi, et al.
Publicado: (2014)

Alcohol imination catalyzed by carbon nanostructures synthesized by C(sp(2))-C(sp(3)) free radical coupling
por: Wang, Cheng, et al.
Publicado: (2023)

A cross-dehydrogenative C(sp(3))−H heteroarylation via photo-induced catalytic chlorine radical generation
por: Huang, Chia-Yu, et al.
Publicado: (2021)

Asymmetric benzylic C(sp(3))−H acylation via dual nickel and photoredox catalysis
por: Huan, Leitao, et al.
Publicado: (2021)

Silver-catalyzed site-selective C(sp(3))−H benzylation of ethers with N-triftosylhydrazones
por: Liu, Zhaohong, et al.
Publicado: (2022)

Catalytic, selective, and stereocontrolled construction of C4 quaternary and homobenzylic dihydroisoquinolones by sp(3) C–H benzylation
por: Beng, Timothy K., et al.
Publicado: (2020)

Non-noble metal-catalyzed cross-dehydrogenation coupling (CDC) involving ether α-C(sp(3))–H to construct C–C bonds
por: Yu, Hui, et al.
Publicado: (2023)

Reductive C(sp(3))–C(sp(3)) homo-coupling of benzyl or allyl halides with H(2) using a water-soluble electron storage catalyst
por: Yatabe, Takeshi, et al.
Publicado: (2021)

Multiple remote C(sp(3))–H functionalizations of aliphatic ketones via bimetallic Cu–Pd catalyzed successive dehydrogenation
por: Li, Hongyi, et al.
Publicado: (2022)

Single operation palladium catalysed C(sp(3))–H functionalisation of tertiary aldehydes: investigations into transient imine directing groups
por: St John-Campbell, S., et al.
Publicado: (2017)

Palladium-catalyzed benzylic C(sp(3))–H carbonylative arylation of azaarylmethyl amines with aryl bromides
por: Zhao, Haoqiang, et al.
Publicado: (2021)

Ligand-free iron-catalyzed benzylic C (sp(3))–H amination of methylarenes with N-fluorobenzenesulfonimide
por: Bao, Fengyu, et al.
Publicado: (2019)

Kinetic resolution of cyclic benzylic azides enabled by site- and enantioselective C(sp(3))–H oxidation
por: Ye, Pengbo, et al.
Publicado: (2022)

Cyclopropane-Fused N-Heterocycles via Aza-Heck-Triggered C(sp(3))–H Functionalization Cascades
por: Jing, Changcheng, et al.
Publicado: (2022)

SO(2)F(2) mediated cascade dehydrogenative Morita–Baylis–Hillman reaction of the C(sp(3))–H of primary alcohols with the C(sp(2))–H of electron-deficient olefins for the assembly of allylic alcohols
por: Jiang, Ying, et al.
Publicado: (2019)

Dehydrogenative C–H Phenochalcogenazination
por: Cremer, Christopher, et al.
Publicado: (2021)

Quantitative evaluation of H-donating abilities of C(sp(3))–H bonds of nitrogen-containing heterocycles in hydrogen atom transfer reaction
por: Fu, Yan-Hua, et al.
Publicado: (2023)

Cobalt-catalyzed C(sp(3))–H/C(sp(2))–H oxidative coupling between alkanes and benzamides
por: Li, Shuangjie, et al.
Publicado: (2018)

Mechanistic and Kinetic Studies of the Direct Alkylation of Benzylic Amines: A Formal C(sp(3))–H Activation Proceeds Actually via a C(sp(2))–H Activation Pathway
por: Pollice, Robert, et al.
Publicado: (2014)

Transition metal-free direct dehydrogenative arylation of activated C(sp(3))–H bonds: synthetic ambit and DFT reactivity predictions
por: Lovato, Kaitlyn, et al.
Publicado: (2018)

Oxidative cross-dehydrogenative coupling (CDC) via C((sp(2)))–H bond functionalization: tert-butyl peroxybenzoate (TBPB)-promoted regioselective direct C-3 acylation/benzoylation of 2H-indazoles with aldehydes/benzyl alcohols/styrenes
por: Sharma, Richa, et al.
Publicado: (2021)

C(sp(3))–H oxygenation via alkoxypalladium(ii) species: an update for the mechanism
por: Zhang, Shuaizhong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ic2p88fk7alm7b6fltnju77599