A chiral cobalt(ii) complex catalyzed enantioselective aza-Piancatelli rearrangement/Diels–Alder cascade reaction

A chiral N,N′-dioxide/cobalt(ii) complex catalyzed highly diastereoselective and enantioselective tandem aza-Piancatelli rearrangement/intramolecular Diels–Alder reaction has been disclosed. Various valuable hexahydro-2a,5-epoxycyclopenta[cd]isoindoles bearing six contiguous stereocenters have been...

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Detalles Bibliográficos
Autores principales: Shen, Bin, He, Qianwen, Dong, Shunxi, Liu, Xiaohua, Feng, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152720/
https://www.ncbi.nlm.nih.gov/pubmed/34122854
http://dx.doi.org/10.1039/d0sc00542h
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author Shen, Bin
He, Qianwen
Dong, Shunxi
Liu, Xiaohua
Feng, Xiaoming
author_facet Shen, Bin
He, Qianwen
Dong, Shunxi
Liu, Xiaohua
Feng, Xiaoming
author_sort Shen, Bin
collection PubMed
description A chiral N,N′-dioxide/cobalt(ii) complex catalyzed highly diastereoselective and enantioselective tandem aza-Piancatelli rearrangement/intramolecular Diels–Alder reaction has been disclosed. Various valuable hexahydro-2a,5-epoxycyclopenta[cd]isoindoles bearing six contiguous stereocenters have been obtained in good yields with excellent diastereo- and enantio-selectivities from a wide range of both readily available 2-furylcarbinols and N-(furan-2-ylmethyl)anilines.
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spelling pubmed-81527202021-06-11 A chiral cobalt(ii) complex catalyzed enantioselective aza-Piancatelli rearrangement/Diels–Alder cascade reaction Shen, Bin He, Qianwen Dong, Shunxi Liu, Xiaohua Feng, Xiaoming Chem Sci Chemistry A chiral N,N′-dioxide/cobalt(ii) complex catalyzed highly diastereoselective and enantioselective tandem aza-Piancatelli rearrangement/intramolecular Diels–Alder reaction has been disclosed. Various valuable hexahydro-2a,5-epoxycyclopenta[cd]isoindoles bearing six contiguous stereocenters have been obtained in good yields with excellent diastereo- and enantio-selectivities from a wide range of both readily available 2-furylcarbinols and N-(furan-2-ylmethyl)anilines. The Royal Society of Chemistry 2020-03-11 /pmc/articles/PMC8152720/ /pubmed/34122854 http://dx.doi.org/10.1039/d0sc00542h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Shen, Bin
He, Qianwen
Dong, Shunxi
Liu, Xiaohua
Feng, Xiaoming
A chiral cobalt(ii) complex catalyzed enantioselective aza-Piancatelli rearrangement/Diels–Alder cascade reaction
title A chiral cobalt(ii) complex catalyzed enantioselective aza-Piancatelli rearrangement/Diels–Alder cascade reaction
title_full A chiral cobalt(ii) complex catalyzed enantioselective aza-Piancatelli rearrangement/Diels–Alder cascade reaction
title_fullStr A chiral cobalt(ii) complex catalyzed enantioselective aza-Piancatelli rearrangement/Diels–Alder cascade reaction
title_full_unstemmed A chiral cobalt(ii) complex catalyzed enantioselective aza-Piancatelli rearrangement/Diels–Alder cascade reaction
title_short A chiral cobalt(ii) complex catalyzed enantioselective aza-Piancatelli rearrangement/Diels–Alder cascade reaction
title_sort chiral cobalt(ii) complex catalyzed enantioselective aza-piancatelli rearrangement/diels–alder cascade reaction
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152720/
https://www.ncbi.nlm.nih.gov/pubmed/34122854
http://dx.doi.org/10.1039/d0sc00542h
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