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Construction of Recombinant Human GM-CSF and GM-CSF-ApoA-I Fusion Protein and Evaluation of Their Biological Activity

In this study, two strains of the yeast P. pastoris were constructed, one of which produced authentic recombinant human granulocyte-macrophage colony-stimulating factor (ryGM-CSF), and the other was a chimera consisting of ryGM-CSF genetically fused with mature human apolipoprotein A-I (ApoA-I) (ryG...

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Detalles Bibliográficos
Autores principales: Pykhtina, Mariya, Miroshnichenko, Svetlana, Romanov, Vladimir, Grazhdantseva, Antonina, Kochneva, Galina, Beklemishev, Anatoly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152757/
https://www.ncbi.nlm.nih.gov/pubmed/34068113
http://dx.doi.org/10.3390/ph14050459