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Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation
The use of vitamin D (VitD) supplements has become widespread in the last decade due not only to the dissociation between the blood levels recommended as “optimal” and those shown by the healthy population but also to its presumed beneficial effects on multiple disorders. This work evaluated the lev...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152961/ https://www.ncbi.nlm.nih.gov/pubmed/34068177 http://dx.doi.org/10.3390/nu13051647 |
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author | García-Dorta, Alicia Medina-Vega, Lillian Villacampa-Jiménez, Jacobo Javier Hernández-Díaz, Marta Bustabad-Reyes, Sagrario González-Dávila, Enrique Díaz-González, Federico |
author_facet | García-Dorta, Alicia Medina-Vega, Lillian Villacampa-Jiménez, Jacobo Javier Hernández-Díaz, Marta Bustabad-Reyes, Sagrario González-Dávila, Enrique Díaz-González, Federico |
author_sort | García-Dorta, Alicia |
collection | PubMed |
description | The use of vitamin D (VitD) supplements has become widespread in the last decade due not only to the dissociation between the blood levels recommended as “optimal” and those shown by the healthy population but also to its presumed beneficial effects on multiple disorders. This work evaluated the levels of 25-hydroxyvitamin D (25(OH)D) in a healthy population of European origin living in a region with high solar irradiation. In serum samples from a population-based study conducted in the Canary Islands, levels of 25(OH)D were analyzed. In 876 individuals who had no history of kidney or malabsorption disorders and, who had not been treated with calcium and/or VitD supplementation, the median 25(OH)D level was 26.3 (5th; 95th percentile, 14.3; 45.8) ng/mL. Notably, 65.4% of the population had 25(OH)D blood levels below 30 ng/mL, 23.4% below 20 ng/mL and 6.4% below 15 ng/mL. Based on the lack of evidence supporting causality between 25(OH)D levels below what is recommended as optimal (≥20 ng/mL, or even ≥30 ng/mL) and major skeletal and non-skeletal diseases, and in light of the distribution of the concentration of this vitamin in healthy adults living under optimal conditions of solar irradiation, it seems reasonable to consider 25(OH)D levels below 20 ng/mL and close to 15 ng/mL as adequate for the general population. |
format | Online Article Text |
id | pubmed-8152961 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81529612021-05-27 Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation García-Dorta, Alicia Medina-Vega, Lillian Villacampa-Jiménez, Jacobo Javier Hernández-Díaz, Marta Bustabad-Reyes, Sagrario González-Dávila, Enrique Díaz-González, Federico Nutrients Article The use of vitamin D (VitD) supplements has become widespread in the last decade due not only to the dissociation between the blood levels recommended as “optimal” and those shown by the healthy population but also to its presumed beneficial effects on multiple disorders. This work evaluated the levels of 25-hydroxyvitamin D (25(OH)D) in a healthy population of European origin living in a region with high solar irradiation. In serum samples from a population-based study conducted in the Canary Islands, levels of 25(OH)D were analyzed. In 876 individuals who had no history of kidney or malabsorption disorders and, who had not been treated with calcium and/or VitD supplementation, the median 25(OH)D level was 26.3 (5th; 95th percentile, 14.3; 45.8) ng/mL. Notably, 65.4% of the population had 25(OH)D blood levels below 30 ng/mL, 23.4% below 20 ng/mL and 6.4% below 15 ng/mL. Based on the lack of evidence supporting causality between 25(OH)D levels below what is recommended as optimal (≥20 ng/mL, or even ≥30 ng/mL) and major skeletal and non-skeletal diseases, and in light of the distribution of the concentration of this vitamin in healthy adults living under optimal conditions of solar irradiation, it seems reasonable to consider 25(OH)D levels below 20 ng/mL and close to 15 ng/mL as adequate for the general population. MDPI 2021-05-13 /pmc/articles/PMC8152961/ /pubmed/34068177 http://dx.doi.org/10.3390/nu13051647 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article García-Dorta, Alicia Medina-Vega, Lillian Villacampa-Jiménez, Jacobo Javier Hernández-Díaz, Marta Bustabad-Reyes, Sagrario González-Dávila, Enrique Díaz-González, Federico Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation |
title | Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation |
title_full | Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation |
title_fullStr | Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation |
title_full_unstemmed | Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation |
title_short | Baseline Levels of Vitamin D in a Healthy Population from a Region with High Solar Irradiation |
title_sort | baseline levels of vitamin d in a healthy population from a region with high solar irradiation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152961/ https://www.ncbi.nlm.nih.gov/pubmed/34068177 http://dx.doi.org/10.3390/nu13051647 |
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