Cargando…

Weighted Gene Co-Expression Network Analysis Reveals Key Genes and Potential Drugs in Abdominal Aortic Aneurysm

Abdominal aortic aneurysm (AAA) is a prevalent aortic disease that causes high mortality due to asymptomatic gradual expansion and sudden rupture. The underlying molecular mechanisms and effective pharmaceutical therapy for preventing AAA progression have not been fully identified. In this study, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kan, Ke-Jia, Guo, Feng, Zhu, Lei, Pallavi, Prama, Sigl, Martin, Keese, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152975/ https://www.ncbi.nlm.nih.gov/pubmed/34068179 http://dx.doi.org/10.3390/biomedicines9050546

Ejemplares similares

Identification of the Key Genes and Potential Therapeutic Compounds for Abdominal Aortic Aneurysm Based on a Weighted Correlation Network Analysis
por: Li, Lin, et al.
Publicado: (2022)

Prevalence of abdominal aortic aneurysm and associated lower extremity artery aneurysm in men hospitalized for suspected or known cardiopulmonary disease
por: Hohneck, Anna, et al.
Publicado: (2019)

Biphasic Effects of Blue Light Irradiation on Human Umbilical Vein Endothelial Cells
por: Kan, Kejia, et al.
Publicado: (2021)

Comprehensive bioinformatics analysis revealed potential key genes and pathways underlying abdominal aortic aneurysm
por: Zhang, Kaijie, et al.
Publicado: (2023)

Screening key genes for abdominal aortic aneurysm based on gene expression omnibus dataset
por: Wan, Li, et al.
Publicado: (2018)

Identification of key genes and pathways in abdominal aortic aneurysm by integrated bioinformatics analysis
por: Liu, Yihai, et al.
Publicado: (2019)

Identification of key genes associated with the human abdominal aortic aneurysm based on the gene expression profile
por: CHEN, XUDONG, et al.
Publicado: (2015)

Combining Bioinformatics Techniques to Study the Key Immune-Related Genes in Abdominal Aortic Aneurysm
por: Nie, Han, et al.
Publicado: (2020)

Identification of crucial genes in abdominal aortic aneurysm by WGCNA
por: Chen, Siliang, et al.
Publicado: (2019)

Gene Expression Profiling in Abdominal Aortic Aneurysms
por: Behrens, Amelie L., et al.
Publicado: (2022)

Key ferroptosis-related genes in abdominal aortic aneurysm formation and rupture as determined by combining bioinformatics techniques
por: Ren, Jinrui, et al.
Publicado: (2022)

Comparison of Genes Associated with Thoracic and Abdominal Aortic Aneurysms
por: Gyftopoulos, Argyrios, et al.
Publicado: (2023)

Dysregulations of Key Regulators of Angiogenesis and Inflammation in Abdominal Aortic Aneurysm
por: Zalewski, Daniel, et al.
Publicado: (2023)

First genetic analysis of aneurysm genes in familial and sporadic abdominal aortic aneurysm
por: van de Luijtgaarden, Koen M., et al.
Publicado: (2015)

Differential gene expression in human abdominal aortic aneurysm and aortic occlusive disease
por: Biros, Erik, et al.
Publicado: (2015)

Identification of MEDAG and SERPINE1 Related to Hypoxia in Abdominal Aortic Aneurysm Based on Weighted Gene Coexpression Network Analysis
por: Teng, Biyun, et al.
Publicado: (2022)

Parallel Murine and Human Aortic Wall Genomics Reveals Metabolic Reprogramming as Key Driver of Abdominal Aortic Aneurysm Progression
por: Gäbel, Gabor, et al.
Publicado: (2021)

Gene Regulatory Network Analysis of Perivascular Adipose Tissue of Abdominal Aortic Aneurysm Identifies Master Regulators of Key Pathogenetic Pathways
por: Piacentini, Luca, et al.
Publicado: (2020)

Identification of key genes in calcific aortic valve disease via weighted gene co-expression network analysis
por: Sun, Jin-Yu, et al.
Publicado: (2021)

General Considerations of Ruptured Abdominal Aortic Aneurysm: Ruptured Abdominal Aortic Aneurysm
por: Lee, Chung Won, et al.
Publicado: (2015)

Ruptured Abdominal Aortic Aneurysm with Antecedent Endovascular Repair of Abdominal Aortic Aneurysm
por: Cho, Jae S.
Publicado: (2014)

Identification of key monocytes/macrophages related gene set of the early-stage abdominal aortic aneurysm by integrated bioinformatics analysis and experimental validation
por: Cheng, Shuai, et al.
Publicado: (2022)

Dysregulation of microRNAs and target genes networks in human abdominal aortic aneurysm tissues
por: de Araujo, Neire Niara Ferreira, et al.
Publicado: (2019)

Identification and experimental validation of autophagy-related genes in abdominal aortic aneurysm
por: Yuan, Xiaoli, et al.
Publicado: (2023)

The potential role of chemotaxis and the complement system in the formation and progression of thoracic aortic aneurysms inferred from the weighted gene coexpression network analysis
por: Lei, Chuxiang, et al.
Publicado: (2021)

Micromanaging Abdominal Aortic Aneurysms
por: Maegdefessel, Lars, et al.
Publicado: (2013)

Giant abdominal aortic aneurysms
por: Ng, Joshua I., et al.
Publicado: (2021)

Mechanosignals in abdominal aortic aneurysms
por: Lowis, Christiana, et al.
Publicado: (2023)

Identification and validation of key genes mediating intracranial aneurysm rupture by weighted correlation network analysis
por: Chen, Siliang, et al.
Publicado: (2020)

Weighted miRNA co-expression network reveals potential roles of apoptosis related pathways and crucial genes in thoracic aortic aneurysm
por: Chen, Siliang, et al.
Publicado: (2021)

Ruptured Abdominal Aortic Aneurysm after Endovascular Aortic Aneurysm Repair
por: Lee, Chung Won, et al.
Publicado: (2011)

Abdominal Aortic Aneurysm: Roles of Inflammatory Cells
por: Yuan, Zhen, et al.
Publicado: (2021)

Bioinformatics analysis of common key genes and pathways of intracranial, abdominal, and thoracic aneurysms
por: Bi, Siwei, et al.
Publicado: (2021)

Automated Screening for Abdominal Aortic Aneurysm in CT Scans under Clinical Conditions Using Deep Learning
por: Golla, Alena-K., et al.
Publicado: (2021)

High-risk factors related to the occurrence and development of abdominal aortic aneurysm
por: Shuai, Tao, et al.
Publicado: (2020)

FRZB as a key molecule in abdominal aortic aneurysm progression affecting vascular integrity
por: Oh, Chang-Kyu, et al.
Publicado: (2021)

Bioinformatics Analysis Reveals the Potential Diagnostic Biomarkers for Abdominal Aortic Aneurysm
por: Xie, Xinsheng, et al.
Publicado: (2021)

Histopathological Characterization of Abdominal Aortic Aneurysms from Patients with Multiple Aneurysms Compared to Patients with a Single Abdominal Aortic Aneurysm
por: Körfer, Daniel, et al.
Publicado: (2023)

T cells in abdominal aortic aneurysm: immunomodulation and clinical application
por: Gong, Wei, et al.
Publicado: (2023)

Experimental Models of Abdominal Aortic Aneurysms
por: Tsui, Janice C
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_bssci5prcbolq181clr82tgmel