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Choline-Sigma-1R as an Additional Mechanism for Potentiation of Orexin by Cocaine
Orexin A, an endogenous peptide involved in several functions including reward, acts via activation of orexin receptors OX(1) and OX(2), Gq-coupled GPCRs. We examined the effect of a selective OX(1) agonist, OXA (17-33) on cytosolic calcium concentration, [Ca(2+)](i), in neurons of nucleus accumbens...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152999/ https://www.ncbi.nlm.nih.gov/pubmed/34068146 http://dx.doi.org/10.3390/ijms22105160 |