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Development of [(225)Ac]Ac-PSMA-I&T for Targeted Alpha Therapy According to GMP Guidelines for Treatment of mCRPC
Recently, promising results of the antitumor effects were observed in patients with metastatic castration-resistant prostate cancer treated with (177)Lu-labeled PSMA-ligands. Radionuclide therapy efficacy may even be improved by using the alpha emitter Ac-225. Higher efficacy is claimed due to high...
Autores principales: | Hooijman, Eline L., Chalashkan, Yozlem, Ling, Sui Wai, Kahyargil, Figen F., Segbers, Marcel, Bruchertseifer, Frank, Morgenstern, Alfred, Seimbille, Yann, Koolen, Stijn L. W., Brabander, Tessa, de Blois, Erik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153125/ https://www.ncbi.nlm.nih.gov/pubmed/34068206 http://dx.doi.org/10.3390/pharmaceutics13050715 |
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