Cargando…

Rac1/Wave2/Arp3 Pathway Mediates Rat Blood-Brain Barrier Dysfunction under Simulated Microgravity Based on Proteomics Strategy

The blood-brain barrier (BBB) is critical to maintaining central nervous system (CNS) homeostasis. However, the effects of microgravity (MG) on the BBB remain unclear. This study aimed to investigate the influence of simulated MG (SMG) on the BBB and explore its potential mechanism using a proteomic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Ranran, Liu, Huayan, Lv, Fang, Deng, Yulin, Li, Yujuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153163/ https://www.ncbi.nlm.nih.gov/pubmed/34068233 http://dx.doi.org/10.3390/ijms22105165

Ejemplares similares

Dragon’s Blood Regulates Rac1-WAVE2-Arp2/3 Signaling Pathway to Protect Rat Intestinal Epithelial Barrier Dysfunction Induced by Simulated Microgravity
por: Li, Yujuan, et al.
Publicado: (2021)

Semen Ziziphi Spinosae attenuates blood–brain barrier dysfunction induced by lipopolysaccharide by targeting the FAK-DOCK180-Rac1-WAVE2-Arp3 signaling pathway
por: Liu, Huayan, et al.
Publicado: (2022)

Investigation on Intestinal Proteins and Drug Metabolizing Enzymes in Simulated Microgravity Rats by a Proteomics Method
por: Liu, Huayan, et al.
Publicado: (2020)

Simulated Microgravity Alters P-Glycoprotein Efflux Function and Expression via the Wnt/β-Catenin Signaling Pathway in Rat Intestine and Brain
por: Liu, Huayan, et al.
Publicado: (2023)

Simulated Microgravity Altered the Metabolism of Loureirin B and the Expression of Major Cytochrome P450 in Liver of Rats
por: Chen, Bo, et al.
Publicado: (2018)

The influence of simulated microgravity on the proteome of Daphnia magna
por: Trotter, Benjamin, et al.
Publicado: (2015)

The mitochondrial proteomic changes of rat hippocampus induced by 28-day simulated microgravity
por: Ji, Guohua, et al.
Publicado: (2022)

The Emerging Role of Macrophages in Immune System Dysfunction under Real and Simulated Microgravity Conditions
por: Sun, Yulong, et al.
Publicado: (2021)

Effects of Simulated Microgravity on the Proteome and Secretome of the Polyextremotolerant Black Fungus Knufia chersonesos
por: Tesei, Donatella, et al.
Publicado: (2021)

Technology using simulated microgravity
por: Nishimura, Yusuke
Publicado: (2023)

Antioxidant Strategy to Prevent Simulated Microgravity-Induced Effects on Bone Osteoblasts
por: Morabito, Caterina, et al.
Publicado: (2020)

Additive effects of simulated microgravity and ionizing radiation in cell death, induction of ROS and expression of RAC2 in human bronchial epithelial cells
por: Tan, Shaobo, et al.
Publicado: (2020)

Sperm Motility of Mice under Simulated Microgravity and Hypergravity
por: Ogneva, Irina V., et al.
Publicado: (2020)

Changes in Vibrio natriegens Growth Under Simulated Microgravity
por: Yin, Man, et al.
Publicado: (2020)

Untargeted Lipidomics of Erythrocytes under Simulated Microgravity Conditions
por: Manis, Cristina, et al.
Publicado: (2023)

Rac and Arp2/3-Nucleated Actin Networks Antagonize Rho During Mitotic and Meiotic Cleavages
por: Pal, Debadrita, et al.
Publicado: (2020)

Data-independent proteome analysis of ARPE-19 cells
por: Koirala, Diwa, et al.
Publicado: (2018)

A Simulated Microgravity Environment Causes a Sustained Defect in Epithelial Barrier Function
por: Alvarez, Rocio, et al.
Publicado: (2019)

YAP Inhibition Alleviates Simulated Microgravity-Induced Mesenchymal Stem Cell Senescence via Targeting Mitochondrial Dysfunction
por: Lv, Wenjun, et al.
Publicado: (2023)

Planarians Sense Simulated Microgravity and Hypergravity
por: Adell, Teresa, et al.
Publicado: (2014)

Simulated microgravity in the ring-sheared drop
por: McMackin, Patrick M., et al.
Publicado: (2020)

The Effects of Simulated Microgravity on Macrophage Phenotype
por: Ludtka, Christopher, et al.
Publicado: (2021)

Adaptation to simulated microgravity in Streptococcus mutans
por: Fernander, Mizpha C., et al.
Publicado: (2022)

In Vitro Growth of Mouse Preantral Follicles Under Simulated Microgravity
por: Zhang, Shen, et al.
Publicado: (2017)

Efficient preservation of sprouting vegetables under simulated microgravity conditions
por: Makino, Yoshio, et al.
Publicado: (2020)

Assessment of the Psychophysiological State of Female Operators Under Simulated Microgravity
por: Lebedeva, Svetlana, et al.
Publicado: (2022)

Sharp Changes in Muscle Tone in Humans Under Simulated Microgravity
por: Amirova, Liubov E., et al.
Publicado: (2021)

Alterations in the activity and sleep of Drosophila melanogaster under simulated microgravity
por: Zhang, Hongying, et al.
Publicado: (2021)

Human gut microbiome and metabolite dynamics under simulated microgravity
por: Ramos-Nascimento, Ana, et al.
Publicado: (2023)

Arp
Publicado: (1988)

ARP3 Controls the Podocyte Architecture at the Kidney Filtration Barrier
por: Schell, Christoph, et al.
Publicado: (2018)

Effects of Simulated Microgravity on Embryonic Stem Cells
por: Wang, Yulan, et al.
Publicado: (2011)

The Impact of Spaceflight and Simulated Microgravity on Cell Adhesion
por: Lin, Xiao, et al.
Publicado: (2020)

Engineered Microvessel for Cell Culture in Simulated Microgravity
por: ElGindi, Mei, et al.
Publicado: (2021)

GxcM-Fbp17/RacC-WASP signaling regulates polarized cortex assembly in migrating cells via Arp2/3
por: Li, Dong, et al.
Publicado: (2023)

Simulated Microgravity Exposure Induces Antioxidant Barrier Deregulation and Mitochondria Enlargement in TCam-2 Cell Spheroids
por: Berardini, Marika, et al.
Publicado: (2023)

Mechanism for enhancing the growth of mung bean seedlings under simulated microgravity
por: Nakajima, Shusaku, et al.
Publicado: (2021)

Colony growth and biofilm formation of Aspergillus niger under simulated microgravity
por: Cortesão, Marta, et al.
Publicado: (2022)

Competition and Synergy of Arp2/3 and Formins in Nucleating Actin Waves
por: Le Chua, Xiang, et al.
Publicado: (2023)

Assessment of automatic ligand building in ARP/wARP
por: Evrard, Guillaume X., et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_f33788boiskd3t00s808rirtnp