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Unprecedented hour-long residence time of a cation in a left-handed G-quadruplex

Cations are critical for the folding and assembly of nucleic acids. In G-quadruplex structures, cations can bind between stacked G-tetrads and coordinate with negatively charged guanine carbonyl oxygens. They usually exchange between binding sites and with the bulk in solution with time constants ra...

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Detalles Bibliográficos
Autores principales: Winnerdy, Fernaldo Richtia, Bakalar, Blaž, Das, Poulomi, Heddi, Brahim, Marchand, Adrien, Rosu, Frédéric, Gabelica, Valérie, Phan, Anh Tuân
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153214/
https://www.ncbi.nlm.nih.gov/pubmed/34123342
http://dx.doi.org/10.1039/d1sc00515d