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3D-visualization of amyloid-β oligomer interactions with lipid membranes by cryo-electron tomography

Amyloid-β (Aβ) assemblies have been shown to bind to lipid bilayers. This can disrupt membrane integrity and cause a loss of cellular homeostasis, that triggers a cascade of events leading to Alzheimer's disease. However, molecular mechanisms of Aβ cytotoxicity and how the different assembly fo...

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Detalles Bibliográficos
Autores principales:	Tian, Yao, Liang, Ruina, Kumar, Amit, Szwedziak, Piotr, Viles, John H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153238/ https://www.ncbi.nlm.nih.gov/pubmed/34123318 http://dx.doi.org/10.1039/d0sc06426b

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