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Boon and Bane of DNA Double-Strand Breaks

DNA double-strand breaks (DSBs), interrupting the genetic information, are elicited by various environmental and endogenous factors. They bear the risk of cell lethality and, if mis-repaired, of deleterious mutation. This negative impact is contrasted by several evolutionary achievements for DSB pro...

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Detalles Bibliográficos
Autor principal: Schubert, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153287/
https://www.ncbi.nlm.nih.gov/pubmed/34068283
http://dx.doi.org/10.3390/ijms22105171