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The nanoscale organization of the Wnt signaling integrator Dishevelled in the vegetal cortex domain of an egg and early embryo

Canonical Wnt/β-catenin (cWnt) signaling is a crucial regulator of development and Dishevelled (Dsh/Dvl) functions as an integral part of this pathway by linking Wnt binding to the Frizzled:LRP5/6 receptor complex with β-catenin-stimulated gene expression. In many cell types Dsh has been localized t...

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Detalles Bibliográficos
Autores principales: Henson, John H., Samasa, Bakary, Shuster, Charles B., Wikramanayake, Athula H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153439/
https://www.ncbi.nlm.nih.gov/pubmed/34038442
http://dx.doi.org/10.1371/journal.pone.0248197

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