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Human-derived Treg and MSC combination therapy may augment immunosuppressive potency in vitro, but did not improve blood brain barrier integrity in an experimental rat traumatic brain injury model
Traumatic brain injury (TBI) causes both physical disruption of the blood brain barrier (BBB) and altered immune responses that can lead to significant secondary brain injury and chronic inflammation within the central nervous system (CNS). Cell therapies, including mesenchymal stromal cells (MSC),...
Autores principales: | Caplan, Henry W., Prabhakara, Karthik S., Toledano Furman, Naama E., Zorofchian, Soheil, Martin, Cecilia, Xue, Hasen, Olson, Scott D., Cox, Charles S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153465/ https://www.ncbi.nlm.nih.gov/pubmed/34038436 http://dx.doi.org/10.1371/journal.pone.0251601 |
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