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LCD-Composer: an intuitive, composition-centric method enabling the identification and detailed functional mapping of low-complexity domains

Low complexity domains (LCDs) in proteins are regions predominantly composed of a small subset of the possible amino acids. LCDs are involved in a variety of normal and pathological processes across all domains of life. Existing methods define LCDs using information-theoretical complexity thresholds...

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Detalles Bibliográficos
Autores principales: Cascarina, Sean M, King, David C, Osborne Nishimura, Erin, Ross, Eric D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153834/
https://www.ncbi.nlm.nih.gov/pubmed/34056598
http://dx.doi.org/10.1093/nargab/lqab048

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