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Molecular Dynamics-Based Allosteric Prediction Method to Design Key Residues in Threonine Dehydrogenase for Amino-Acid Production

[Image: see text] Allosteric proteins are considered as one of the most critical targets to design cell factories via synthetic biology approaches. Here, we proposed a molecular dynamics-based allosteric prediction method (MBAP) to screen indirect-binding sites and potential mutations for protein re...

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Detalles Bibliográficos
Autores principales: Wu, Mingyu, Sun, Yu, Zhu, Meiru, Zhu, Laiyu, Lü, Junhong, Geng, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153896/
https://www.ncbi.nlm.nih.gov/pubmed/34056250
http://dx.doi.org/10.1021/acsomega.1c00798

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