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Substrate Specificity and Biochemical Characteristics of an Engineered Mammalian Chondroitinase ABC
[Image: see text] Chondroitin sulfate proteoglycans inhibit regeneration, neuroprotection, and plasticity following spinal cord injury. The development of a second-generation chondroitinase ABC enzyme, capable of being secreted from mammalian cells (mChABC), has facilitated the functional recovery o...
Autores principales: | Warren, Philippa M., Fawcett, James W., Kwok, Jessica C. F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153898/ https://www.ncbi.nlm.nih.gov/pubmed/34056277 http://dx.doi.org/10.1021/acsomega.0c06262 |
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