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Sulfonated Nonsaccharide Heparin Mimetics Are Potent and Noncompetitive Inhibitors of Human Neutrophil Elastase

[Image: see text] Human neutrophil elastase (HNE) is a serine protease that plays vital roles in inflammation, innate immune response, and tissue remodeling processes. HNE has been actively pursued as a drug target, particularly for the treatment of cardiopulmonary diseases. Although thousands of mo...

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Detalles Bibliográficos
Autores principales:	Al-Horani, Rami A., Aliter, Kholoud F., Kar, Srabani, Mottamal, Madhusoodanan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154244/ https://www.ncbi.nlm.nih.gov/pubmed/34056422 http://dx.doi.org/10.1021/acsomega.1c00935

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