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Predicting the propagation of COVID-19 at an international scale: extension of an SIR model

OBJECTIVES: Several epidemiological models have been published to forecast the spread of the COVID-19 pandemic, yet many of them have proven inaccurate for reasons that remain to be fully determined. We aimed to develop a novel model and implement it in a freely accessible web application. DESIGN: W...

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Autores principales: Lavielle, Marc, Faron, Matthieu, Lefevre, Jérémie H, Zeitoun, Jean-David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154292/
https://www.ncbi.nlm.nih.gov/pubmed/34035086
http://dx.doi.org/10.1136/bmjopen-2020-041472
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author Lavielle, Marc
Faron, Matthieu
Lefevre, Jérémie H
Zeitoun, Jean-David
author_facet Lavielle, Marc
Faron, Matthieu
Lefevre, Jérémie H
Zeitoun, Jean-David
author_sort Lavielle, Marc
collection PubMed
description OBJECTIVES: Several epidemiological models have been published to forecast the spread of the COVID-19 pandemic, yet many of them have proven inaccurate for reasons that remain to be fully determined. We aimed to develop a novel model and implement it in a freely accessible web application. DESIGN: We built an SIR-type compartmental model with two additional compartments: D (deceased patients); L (individuals who will die but who will not infect anybody due to social or medical isolation) and integration of a time-dependent transmission rate and a periodical weekly component linked to the way in which cases and deaths are reported. RESULTS: The model was implemented in a web application (as of 2 June 2020). It was shown to be able to accurately capture the changes in the dynamics of the pandemic for 20 countries whatever the type of pandemic spread or containment measures: for instance, the model explains 97% of the variance of US data (daily cases) and predicts the number of deaths at a 2-week horizon with an error of 1%. CONCLUSIONS: In early performance evaluation, our model showed a high level of accuracy between prediction and observed data. Such a tool might be used by the global community to follow the spread of the pandemic.
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spelling pubmed-81542922021-06-02 Predicting the propagation of COVID-19 at an international scale: extension of an SIR model Lavielle, Marc Faron, Matthieu Lefevre, Jérémie H Zeitoun, Jean-David BMJ Open Epidemiology OBJECTIVES: Several epidemiological models have been published to forecast the spread of the COVID-19 pandemic, yet many of them have proven inaccurate for reasons that remain to be fully determined. We aimed to develop a novel model and implement it in a freely accessible web application. DESIGN: We built an SIR-type compartmental model with two additional compartments: D (deceased patients); L (individuals who will die but who will not infect anybody due to social or medical isolation) and integration of a time-dependent transmission rate and a periodical weekly component linked to the way in which cases and deaths are reported. RESULTS: The model was implemented in a web application (as of 2 June 2020). It was shown to be able to accurately capture the changes in the dynamics of the pandemic for 20 countries whatever the type of pandemic spread or containment measures: for instance, the model explains 97% of the variance of US data (daily cases) and predicts the number of deaths at a 2-week horizon with an error of 1%. CONCLUSIONS: In early performance evaluation, our model showed a high level of accuracy between prediction and observed data. Such a tool might be used by the global community to follow the spread of the pandemic. BMJ Publishing Group 2021-05-25 /pmc/articles/PMC8154292/ /pubmed/34035086 http://dx.doi.org/10.1136/bmjopen-2020-041472 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Epidemiology
Lavielle, Marc
Faron, Matthieu
Lefevre, Jérémie H
Zeitoun, Jean-David
Predicting the propagation of COVID-19 at an international scale: extension of an SIR model
title Predicting the propagation of COVID-19 at an international scale: extension of an SIR model
title_full Predicting the propagation of COVID-19 at an international scale: extension of an SIR model
title_fullStr Predicting the propagation of COVID-19 at an international scale: extension of an SIR model
title_full_unstemmed Predicting the propagation of COVID-19 at an international scale: extension of an SIR model
title_short Predicting the propagation of COVID-19 at an international scale: extension of an SIR model
title_sort predicting the propagation of covid-19 at an international scale: extension of an sir model
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154292/
https://www.ncbi.nlm.nih.gov/pubmed/34035086
http://dx.doi.org/10.1136/bmjopen-2020-041472
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