Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni

[Image: see text] Nine hundred million people are infected with the soil-transmitted helminths Ascaris lumbricoides (roundworm), hookworm, and Trichuris trichiura (whipworm). However, low single-dose cure rates of the benzimidazole drugs, the mainstay of preventative chemotherapy for whipworm, toget...

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Detalles Bibliográficos
Autores principales: Partridge, Frederick A., Bataille, Carole J.R., Forman, Ruth, Marriott, Amy E., Forde-Thomas, Josephine, Häberli, Cécile, Dinsdale, Ria L., O’Sullivan, James D.B., Willis, Nicky J., Wynne, Graham M., Whiteland, Helen, Archer, John, Steven, Andrew, Keiser, Jennifer, Turner, Joseph D., Hoffmann, Karl F., Taylor, Mark J., Else, Kathryn J., Russell, Angela J., Sattelle, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154432/
https://www.ncbi.nlm.nih.gov/pubmed/33797218
http://dx.doi.org/10.1021/acsinfecdis.1c00025

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