A Mixed-chimerism Protocol Utilizing Thymoglobulin and Belatacept Did Not Induce Lung Allograft Tolerance, Despite Previous Success in Renal Allotransplantation

BACKGROUND. In kidney transplantation, long-term allograft acceptance in cynomolgus macaques was achieved using a mixed-chimerism protocol based on the clinically available reagents, rabbit anti-thymocyte globulin (ATG), and belatacept. Here, we have tested the same protocol in cynomolgus macaques t...

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Detalles Bibliográficos
Autores principales: Sommer, Wiebke, O, Jane M., Pruner, Kurt B., Dehnadi, Abbas, Ha Huh, Kyu, Robinson, Kortney A., Hanekamp, Isabel, Rosales, Ivy, Bean, Alison S., Paster, Josh, Oura, Tetsu, Neal Smith, Rex, Colvin, Robert, Benichou, Gilles, Kawai, Tatsuo, Madsen, Joren C., Allan, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Lung Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154498/
https://www.ncbi.nlm.nih.gov/pubmed/34056080
http://dx.doi.org/10.1097/TXD.0000000000001150

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