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Psychosocial risk factors associated with esophageal cancer in Chinese cohort: A systematic review and meta-analysis

Previous studies were controversial about the role of psychosocial factors in the pathogenesis of esophageal cancer (EC). This study aimed to systematically evaluate the effect size of psychosocial risk factors for EC in Chinese cohort. A literature search was conducted in both English and Chinese d...

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Autores principales: Lei, Lei, Zhou, Xiang-Yu, Xiang, Li-Li, Xiang, Jie, Li, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154499/
https://www.ncbi.nlm.nih.gov/pubmed/34032723
http://dx.doi.org/10.1097/MD.0000000000026029
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author Lei, Lei
Zhou, Xiang-Yu
Xiang, Li-Li
Xiang, Jie
Li, Xu
author_facet Lei, Lei
Zhou, Xiang-Yu
Xiang, Li-Li
Xiang, Jie
Li, Xu
author_sort Lei, Lei
collection PubMed
description Previous studies were controversial about the role of psychosocial factors in the pathogenesis of esophageal cancer (EC). This study aimed to systematically evaluate the effect size of psychosocial risk factors for EC in Chinese cohort. A literature search was conducted in both English and Chinese databases, and odds ratios (OR) with the corresponding 95% confidence intervals (CI) were pooled using a random-effects model. 28 studies were identified with a total of 6951 EC cases and 7469 controls. The meta-analysis indicated a higher risk of EC among the individuals with psychological trauma (OR: 2.36, 95% CI: 1.71–3.26), Type A behavior (OR: 1.40, 95% CI: 1.17–1.67), depression (OR: 4.00, 95% CI: 2.44–6.55), melancholy (OR: 2.06, 95% CI: 1.32–3.20), always in sulks (OR: 2.49, 95% CI: 1.21–5.12), and irritable personality (OR: 2.13, 95% CI: 1.58–2.89). A lower EC risk was found in the individuals with good interpersonal relationship (OR: 0.35, 95% CI: 0.17–0.70) and outgoing personality (OR: 0.39, 95% CI: 0.19–0.78). This meta-analysis suggested a potential association between psychosocial factors and EC risk. For the individuals with psychosocial risk factors, physicians should pay more attention to EC screening.
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spelling pubmed-81544992021-05-29 Psychosocial risk factors associated with esophageal cancer in Chinese cohort: A systematic review and meta-analysis Lei, Lei Zhou, Xiang-Yu Xiang, Li-Li Xiang, Jie Li, Xu Medicine (Baltimore) 4500 Previous studies were controversial about the role of psychosocial factors in the pathogenesis of esophageal cancer (EC). This study aimed to systematically evaluate the effect size of psychosocial risk factors for EC in Chinese cohort. A literature search was conducted in both English and Chinese databases, and odds ratios (OR) with the corresponding 95% confidence intervals (CI) were pooled using a random-effects model. 28 studies were identified with a total of 6951 EC cases and 7469 controls. The meta-analysis indicated a higher risk of EC among the individuals with psychological trauma (OR: 2.36, 95% CI: 1.71–3.26), Type A behavior (OR: 1.40, 95% CI: 1.17–1.67), depression (OR: 4.00, 95% CI: 2.44–6.55), melancholy (OR: 2.06, 95% CI: 1.32–3.20), always in sulks (OR: 2.49, 95% CI: 1.21–5.12), and irritable personality (OR: 2.13, 95% CI: 1.58–2.89). A lower EC risk was found in the individuals with good interpersonal relationship (OR: 0.35, 95% CI: 0.17–0.70) and outgoing personality (OR: 0.39, 95% CI: 0.19–0.78). This meta-analysis suggested a potential association between psychosocial factors and EC risk. For the individuals with psychosocial risk factors, physicians should pay more attention to EC screening. Lippincott Williams & Wilkins 2021-05-28 /pmc/articles/PMC8154499/ /pubmed/34032723 http://dx.doi.org/10.1097/MD.0000000000026029 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle 4500
Lei, Lei
Zhou, Xiang-Yu
Xiang, Li-Li
Xiang, Jie
Li, Xu
Psychosocial risk factors associated with esophageal cancer in Chinese cohort: A systematic review and meta-analysis
title Psychosocial risk factors associated with esophageal cancer in Chinese cohort: A systematic review and meta-analysis
title_full Psychosocial risk factors associated with esophageal cancer in Chinese cohort: A systematic review and meta-analysis
title_fullStr Psychosocial risk factors associated with esophageal cancer in Chinese cohort: A systematic review and meta-analysis
title_full_unstemmed Psychosocial risk factors associated with esophageal cancer in Chinese cohort: A systematic review and meta-analysis
title_short Psychosocial risk factors associated with esophageal cancer in Chinese cohort: A systematic review and meta-analysis
title_sort psychosocial risk factors associated with esophageal cancer in chinese cohort: a systematic review and meta-analysis
topic 4500
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154499/
https://www.ncbi.nlm.nih.gov/pubmed/34032723
http://dx.doi.org/10.1097/MD.0000000000026029
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