Rhabdomyolysis and severe biphasic disturbance of calcium homeostasis secondary to COVID-19 infection

We report a case of severe hypercalcaemia secondary to rhabdomyolysis in a woman with COVID-19 (SARS CoV-2) infection. The patient presented with myalgia and anuria with an acute kidney injury requiring haemodialysis. Creatine kinase peaked at 760 000 IU/L. A biphasic calcaemic response was observed...

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Autores principales: Li, Adrian Po Zhu, Thomas, Stephen, Gokmen, Refik, Kariyawasam, Dulmini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154693/
https://www.ncbi.nlm.nih.gov/pubmed/34031067
http://dx.doi.org/10.1136/bcr-2020-239611
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author Li, Adrian Po Zhu
Thomas, Stephen
Gokmen, Refik
Kariyawasam, Dulmini
author_facet Li, Adrian Po Zhu
Thomas, Stephen
Gokmen, Refik
Kariyawasam, Dulmini
author_sort Li, Adrian Po Zhu
collection PubMed
description We report a case of severe hypercalcaemia secondary to rhabdomyolysis in a woman with COVID-19 (SARS CoV-2) infection. The patient presented with myalgia and anuria with an acute kidney injury requiring haemodialysis. Creatine kinase peaked at 760 000 IU/L. A biphasic calcaemic response was observed with initial severe hypocalcaemia followed by severe, symptomatic hypercalcaemia, persistent despite haemodialysis. Control of the calcium levels was achieved by continuous haemofiltration.
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spelling pubmed-81546932021-06-09 Rhabdomyolysis and severe biphasic disturbance of calcium homeostasis secondary to COVID-19 infection Li, Adrian Po Zhu Thomas, Stephen Gokmen, Refik Kariyawasam, Dulmini BMJ Case Rep Case Report We report a case of severe hypercalcaemia secondary to rhabdomyolysis in a woman with COVID-19 (SARS CoV-2) infection. The patient presented with myalgia and anuria with an acute kidney injury requiring haemodialysis. Creatine kinase peaked at 760 000 IU/L. A biphasic calcaemic response was observed with initial severe hypocalcaemia followed by severe, symptomatic hypercalcaemia, persistent despite haemodialysis. Control of the calcium levels was achieved by continuous haemofiltration. BMJ Publishing Group 2021-05-24 /pmc/articles/PMC8154693/ /pubmed/34031067 http://dx.doi.org/10.1136/bcr-2020-239611 Text en © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. https://bmj.com/coronavirus/usageThis article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.
spellingShingle Case Report
Li, Adrian Po Zhu
Thomas, Stephen
Gokmen, Refik
Kariyawasam, Dulmini
Rhabdomyolysis and severe biphasic disturbance of calcium homeostasis secondary to COVID-19 infection
title Rhabdomyolysis and severe biphasic disturbance of calcium homeostasis secondary to COVID-19 infection
title_full Rhabdomyolysis and severe biphasic disturbance of calcium homeostasis secondary to COVID-19 infection
title_fullStr Rhabdomyolysis and severe biphasic disturbance of calcium homeostasis secondary to COVID-19 infection
title_full_unstemmed Rhabdomyolysis and severe biphasic disturbance of calcium homeostasis secondary to COVID-19 infection
title_short Rhabdomyolysis and severe biphasic disturbance of calcium homeostasis secondary to COVID-19 infection
title_sort rhabdomyolysis and severe biphasic disturbance of calcium homeostasis secondary to covid-19 infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154693/
https://www.ncbi.nlm.nih.gov/pubmed/34031067
http://dx.doi.org/10.1136/bcr-2020-239611
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AT gokmenrefik rhabdomyolysisandseverebiphasicdisturbanceofcalciumhomeostasissecondarytocovid19infection
AT kariyawasamdulmini rhabdomyolysisandseverebiphasicdisturbanceofcalciumhomeostasissecondarytocovid19infection

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