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Treatment scheduling effects on the evolution of drug resistance in heterogeneous cancer cell populations

The effect of scheduling of targeted therapy combinations on drug resistance is underexplored in triple-negative breast cancer (TNBC). TNBC constitutes heterogeneous cancer cell populations the composition of which can change dynamically during treatment resulting in the selection of resistant clone...

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Detalles Bibliográficos
Autores principales: Patwardhan, Gauri A., Marczyk, Michal, Wali, Vikram B., Stern, David F., Pusztai, Lajos, Hatzis, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154902/
https://www.ncbi.nlm.nih.gov/pubmed/34040000
http://dx.doi.org/10.1038/s41523-021-00270-4