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Treatment scheduling effects on the evolution of drug resistance in heterogeneous cancer cell populations
The effect of scheduling of targeted therapy combinations on drug resistance is underexplored in triple-negative breast cancer (TNBC). TNBC constitutes heterogeneous cancer cell populations the composition of which can change dynamically during treatment resulting in the selection of resistant clone...
Autores principales: | Patwardhan, Gauri A., Marczyk, Michal, Wali, Vikram B., Stern, David F., Pusztai, Lajos, Hatzis, Christos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154902/ https://www.ncbi.nlm.nih.gov/pubmed/34040000 http://dx.doi.org/10.1038/s41523-021-00270-4 |
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