Understanding T cell phenotype for the design of effective chimeric antigen receptor T cell therapies

Rapid advances in immunotherapy have identified adoptive cell transfer as one of the most promising approaches for the treatment of cancers. Large numbers of cancer reactive T lymphocytes can be generated ex vivo from patient blood by genetic modification to express chimeric antigen receptors (CAR)...

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Detalles Bibliográficos
Autores principales: Tantalo, Daniela GM, Oliver, Amanda J, von Scheidt, Bianca, Harrison, Aaron J, Mueller, Scott N, Kershaw, Michael H, Slaney, Clare Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154965/
https://www.ncbi.nlm.nih.gov/pubmed/34035114
http://dx.doi.org/10.1136/jitc-2021-002555

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