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Immunogenicity in humans of a transdermal multipeptide melanoma vaccine administered with or without a TLR7 agonist
BACKGROUND: Experimental cancer vaccines are traditionally administered by injection in subcutaneous tissue or muscle, commonly with adjuvants that create chronic inflammatory depots. Injection of melanoma-derived peptides induces T cell responses; however, the depots that form following injection m...
Autores principales: | Meneveau, Max O, Petroni, Gina R, Salerno, Elise P, Lynch, Kevin T, Smolkin, Mark, Woodson, Elizabeth, Chianese-Bullock, Kimberly A, Olson, Walter C, Deacon, Donna, Patterson, James W, Grosh, William W, Slingluff, Craig L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154977/ https://www.ncbi.nlm.nih.gov/pubmed/34035112 http://dx.doi.org/10.1136/jitc-2020-002214 |
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