HDAC6 inhibitors sensitize non-mesenchymal triple-negative breast cancer cells to cysteine deprivation

Triple-negative breast cancer (TNBC) is a highly malignant type of breast cancer and lacks effective therapy. Targeting cysteine-dependence is an emerging strategy to treat the mesenchymal TNBC. However, many TNBC cells are non-mesenchymal and unresponsive to cysteine deprivation. To overcome such r...

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Detalles Bibliográficos
Autores principales: Alothaim, Tahiyat, Charbonneau, Morgan, Tang, Xiaohu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155140/
https://www.ncbi.nlm.nih.gov/pubmed/34040090
http://dx.doi.org/10.1038/s41598-021-90527-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155140/
https://www.ncbi.nlm.nih.gov/pubmed/34040090
http://dx.doi.org/10.1038/s41598-021-90527-6

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