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Reduced adaptation of glutamatergic stress response is associated with pessimistic expectations in depression

Stress is a significant risk factor for the development of major depressive disorder (MDD), yet the underlying mechanisms remain unclear. Preclinically, adaptive and maladaptive stress-induced changes in glutamatergic function have been observed in the medial prefrontal cortex (mPFC). Here, we exami...

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Detalles Bibliográficos
Autores principales:	Cooper, Jessica A., Nuutinen, Makiah R., Lawlor, Victoria M., DeVries, Brittany A. M., Barrick, Elyssa M., Hossein, Shabnam, Cole, Daniel J., Leonard, Chelsea V., Hahn, Emma C., Teer, Andrew P., Shields, Grant S., Slavich, George M., Ongur, Dost, Jensen, J. Eric, Du, Fei, Pizzagalli, Diego A., Treadway, Michael T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155144/ https://www.ncbi.nlm.nih.gov/pubmed/34039978 http://dx.doi.org/10.1038/s41467-021-23284-9

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