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Chronic cranial window for photoacoustic imaging: a mini review
Photoacoustic (PA) microscopy is being increasingly used to visualize the microcirculation of the brain cortex at the micron level in living rodents. By combining it with long-term cranial window techniques, vasculature can be monitored over a period of days extending to months through a field of vi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155166/ https://www.ncbi.nlm.nih.gov/pubmed/34037873 http://dx.doi.org/10.1186/s42492-021-00081-1 |
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author | Wang, Yongchao Xi, Lei |
author_facet | Wang, Yongchao Xi, Lei |
author_sort | Wang, Yongchao |
collection | PubMed |
description | Photoacoustic (PA) microscopy is being increasingly used to visualize the microcirculation of the brain cortex at the micron level in living rodents. By combining it with long-term cranial window techniques, vasculature can be monitored over a period of days extending to months through a field of view. To fulfill the requirements of long-term in vivo PA imaging, the cranial window must involve a simple and rapid surgical procedure, biological compatibility, and sufficient optical-acoustic transparency, which are major challenges. Recently, several cranial window techniques have been reported for longitudinal PA imaging. Here, the development of chronic cranial windows for PA imaging is reviewed and its technical details are discussed, including window installation, imaging quality, and longitudinal stability. |
format | Online Article Text |
id | pubmed-8155166 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Singapore |
record_format | MEDLINE/PubMed |
spelling | pubmed-81551662021-06-17 Chronic cranial window for photoacoustic imaging: a mini review Wang, Yongchao Xi, Lei Vis Comput Ind Biomed Art Review Photoacoustic (PA) microscopy is being increasingly used to visualize the microcirculation of the brain cortex at the micron level in living rodents. By combining it with long-term cranial window techniques, vasculature can be monitored over a period of days extending to months through a field of view. To fulfill the requirements of long-term in vivo PA imaging, the cranial window must involve a simple and rapid surgical procedure, biological compatibility, and sufficient optical-acoustic transparency, which are major challenges. Recently, several cranial window techniques have been reported for longitudinal PA imaging. Here, the development of chronic cranial windows for PA imaging is reviewed and its technical details are discussed, including window installation, imaging quality, and longitudinal stability. Springer Singapore 2021-05-26 /pmc/articles/PMC8155166/ /pubmed/34037873 http://dx.doi.org/10.1186/s42492-021-00081-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Review Wang, Yongchao Xi, Lei Chronic cranial window for photoacoustic imaging: a mini review |
title | Chronic cranial window for photoacoustic imaging: a mini review |
title_full | Chronic cranial window for photoacoustic imaging: a mini review |
title_fullStr | Chronic cranial window for photoacoustic imaging: a mini review |
title_full_unstemmed | Chronic cranial window for photoacoustic imaging: a mini review |
title_short | Chronic cranial window for photoacoustic imaging: a mini review |
title_sort | chronic cranial window for photoacoustic imaging: a mini review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155166/ https://www.ncbi.nlm.nih.gov/pubmed/34037873 http://dx.doi.org/10.1186/s42492-021-00081-1 |
work_keys_str_mv | AT wangyongchao chroniccranialwindowforphotoacousticimagingaminireview AT xilei chroniccranialwindowforphotoacousticimagingaminireview |