The Cholinergic and ACE-2-Dependent Anti-Inflammatory Systems in the Lung: New Scenarios Emerging From COVID-19

The renin angiotensin system and the cholinergic anti-inflammatory pathway have been recently shown to modulate lung inflammation in patients with COVID-19. We will show how studies performed on this disease are starting to provide evidence that these two anti-inflammatory systems may functionally i...

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Autores principales: Di Maro, Martina, Cataldi, Mauro, Santillo, Mariarosaria, Chiurazzi, Martina, Damiano, Simona, De Conno, Barbara, Colantuoni, Antonio, Guida, Bruna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155253/
https://www.ncbi.nlm.nih.gov/pubmed/34054572
http://dx.doi.org/10.3389/fphys.2021.653985
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author Di Maro, Martina
Cataldi, Mauro
Santillo, Mariarosaria
Chiurazzi, Martina
Damiano, Simona
De Conno, Barbara
Colantuoni, Antonio
Guida, Bruna
author_facet Di Maro, Martina
Cataldi, Mauro
Santillo, Mariarosaria
Chiurazzi, Martina
Damiano, Simona
De Conno, Barbara
Colantuoni, Antonio
Guida, Bruna
author_sort Di Maro, Martina
collection PubMed
description The renin angiotensin system and the cholinergic anti-inflammatory pathway have been recently shown to modulate lung inflammation in patients with COVID-19. We will show how studies performed on this disease are starting to provide evidence that these two anti-inflammatory systems may functionally interact with each other, a mechanism that could have a more general physiological relevance than only COVID-19 infection.
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spelling pubmed-81552532021-05-28 The Cholinergic and ACE-2-Dependent Anti-Inflammatory Systems in the Lung: New Scenarios Emerging From COVID-19 Di Maro, Martina Cataldi, Mauro Santillo, Mariarosaria Chiurazzi, Martina Damiano, Simona De Conno, Barbara Colantuoni, Antonio Guida, Bruna Front Physiol Physiology The renin angiotensin system and the cholinergic anti-inflammatory pathway have been recently shown to modulate lung inflammation in patients with COVID-19. We will show how studies performed on this disease are starting to provide evidence that these two anti-inflammatory systems may functionally interact with each other, a mechanism that could have a more general physiological relevance than only COVID-19 infection. Frontiers Media S.A. 2021-05-13 /pmc/articles/PMC8155253/ /pubmed/34054572 http://dx.doi.org/10.3389/fphys.2021.653985 Text en Copyright © 2021 Di Maro, Cataldi, Santillo, Chiurazzi, Damiano, De Conno, Colantuoni and Guida. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Di Maro, Martina
Cataldi, Mauro
Santillo, Mariarosaria
Chiurazzi, Martina
Damiano, Simona
De Conno, Barbara
Colantuoni, Antonio
Guida, Bruna
The Cholinergic and ACE-2-Dependent Anti-Inflammatory Systems in the Lung: New Scenarios Emerging From COVID-19
title The Cholinergic and ACE-2-Dependent Anti-Inflammatory Systems in the Lung: New Scenarios Emerging From COVID-19
title_full The Cholinergic and ACE-2-Dependent Anti-Inflammatory Systems in the Lung: New Scenarios Emerging From COVID-19
title_fullStr The Cholinergic and ACE-2-Dependent Anti-Inflammatory Systems in the Lung: New Scenarios Emerging From COVID-19
title_full_unstemmed The Cholinergic and ACE-2-Dependent Anti-Inflammatory Systems in the Lung: New Scenarios Emerging From COVID-19
title_short The Cholinergic and ACE-2-Dependent Anti-Inflammatory Systems in the Lung: New Scenarios Emerging From COVID-19
title_sort cholinergic and ace-2-dependent anti-inflammatory systems in the lung: new scenarios emerging from covid-19
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155253/
https://www.ncbi.nlm.nih.gov/pubmed/34054572
http://dx.doi.org/10.3389/fphys.2021.653985
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