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The Golgi as a “Proton Sink” in Cancer

Cancer cells exhibit increased glycolytic flux and adenosine triphosphate (ATP) hydrolysis. These processes increase the acidic burden on the cells through the production of lactate and protons. Nonetheless, cancer cells can maintain an alkaline intracellular pH (pHi) relative to untransformed cells...

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Detalles Bibliográficos
Autores principales: Galenkamp, Koen M. O., Commisso, Cosimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155353/
https://www.ncbi.nlm.nih.gov/pubmed/34055797
http://dx.doi.org/10.3389/fcell.2021.664295