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The Golgi as a “Proton Sink” in Cancer
Cancer cells exhibit increased glycolytic flux and adenosine triphosphate (ATP) hydrolysis. These processes increase the acidic burden on the cells through the production of lactate and protons. Nonetheless, cancer cells can maintain an alkaline intracellular pH (pHi) relative to untransformed cells...
Autores principales: | Galenkamp, Koen M. O., Commisso, Cosimo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155353/ https://www.ncbi.nlm.nih.gov/pubmed/34055797 http://dx.doi.org/10.3389/fcell.2021.664295 |
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