Cargando…

Influence of ABCB1 gene polymorphism on concentration to dose ratio and adverse effects of tacrolimus in Pakistani liver transplant recipients

OBJECTIVE: To evaluate the possible association of ABCB1 single nucleotide polymorphism (SNPs) of the ABCB1 gene with tacrolimus dosages, concentration-to-dose ratios (CDR) and adverse effects in Pakistani liver transplant recipients. METHODS: This observational study was conducted at Shifa Internat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Azam, Fahad, Khan, Moosa, Khaliq, Tanwir, Bhatti, Abu Bakar Hafeez
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Professional Medical Publications 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155444/ https://www.ncbi.nlm.nih.gov/pubmed/34104149 http://dx.doi.org/10.12669/pjms.37.3.3898

Ejemplares similares

Effect of CYP3A4 and PPARA polymorphism on concentration-to-dose ratio and adverse effects of tacrolimus in Pakistani liver transplant recipients
por: Azam, Fahad, et al.
Publicado: (2022)

Effects of ABCB1 DNA methylation in donors on tacrolimus blood concentrations in recipients following liver transplantation
por: Shi, Chengcheng, et al.
Publicado: (2022)

Survival outcome of malignant minor salivary tumors in Pakistani population
por: Iqbal, Hassan, et al.
Publicado: (2014)

Influence of CYP3A5 and ABCB1 Polymorphism on Tacrolimus Drug Dosing in South Indian Renal Allograft Recipients
por: Fernando, M. Edwin, et al.
Publicado: (2019)

Lack of impact of OCTN1 gene polymorphisms on clinical outcomes of gabapentinoids in Pakistani patients with neuropathic pain
por: Shaheen, Abida, et al.
Publicado: (2022)

CYP3A5 and ABCB1 genotype influence tacrolimus and sirolimus pharmacokinetics in renal transplant recipients
por: Li, Yi, et al.
Publicado: (2015)

A non-randomized trial of conversion from ciclosporin and tacrolimus to tacrolimus MR4 in stable long-term kidney transplant recipients: Graft function and influences of ABCB1 genotypes
por: Riegersperger, Markus, et al.
Publicado: (2019)

Effects of Wuzhi Capsules on Blood Concentration of Tacrolimus in Renal Transplant Recipients
por: Yan, Lin, et al.
Publicado: (2019)

Evaluation of clotrimazole prophylaxis on tacrolimus trough concentrations in kidney transplant recipients
por: Wings, Emily, et al.
Publicado: (2022)

Beyond Single Nucleotide Polymorphisms: CYP3A5(∗)3(∗)6(∗)7 Composite and ABCB1 Haplotype Associations to Tacrolimus Pharmacokinetics in Black and White Renal Transplant Recipients
por: Brazeau, Daniel A., et al.
Publicado: (2020)

The effect of ABCB1 polymorphism on sirolimus in renal transplant recipients: a meta-analysis
por: Shao, Shuai, et al.
Publicado: (2020)

Gut microbiome modulates tacrolimus pharmacokinetics through the transcriptional regulation of ABCB1
por: Degraeve, Alexandra L., et al.
Publicado: (2023)

Monitoring the Intracellular Tacrolimus Concentration in Kidney Transplant Recipients with Stable Graft Function
por: Han, Seung Seok, et al.
Publicado: (2016)

Monitoring the tacrolimus concentration in peripheral blood mononuclear cells of kidney transplant recipients
por: Francke, Marith I., et al.
Publicado: (2020)

SARS-CoV-2 and Tacrolimus Blood Concentration in Kidney Transplant Recipients
por: McMinn, Jason, et al.
Publicado: (2021)

Effect of Concentration/Dose Ratio in De Novo Kidney Transplant Recipients Receiving LCP-Tacrolimus or Immediate-Release Tacrolimus: Post Hoc Analysis of a Phase 3 Clinical Trial
por: Suwelack, Barbara, et al.
Publicado: (2020)

Brain/blood ratios of methadone and ABCB1 polymorphisms in methadone-related deaths
por: Iwersen-Bergmann, S., et al.
Publicado: (2021)

Donor CYP3A5 Gene Polymorphism Alone Cannot Predict Tacrolimus Intrarenal Concentration in Renal Transplant Recipients
por: Zhang, Mengyu, et al.
Publicado: (2020)

Personalized Tacrolimus Dose Requirement by CYP3A5 but Not ABCB1 or ACE Genotyping in Both Recipient and Donor after Pediatric Liver Transplantation
por: Chen, Yi-kuan, et al.
Publicado: (2014)

APOE Gene Polymorphism and Risk of Coronary Stenosis in Pakistani Population
por: Cheema, Asma Naseer, et al.
Publicado: (2015)

Pharmacokinetic profiles of significant adverse events with crizotinib in Japanese patients with ABCB1 polymorphism
por: Fujiwara, Yutaka, et al.
Publicado: (2016)

CYP3A5 polymorphisms in renal transplant recipients: influence on tacrolimus treatment
por: Chen, Lucy, et al.
Publicado: (2018)

Association of IGF1 polymorphisms with exotropia in a Pakistani cohort
por: Zehra, Zainab, et al.
Publicado: (2022)

Pakistani and CERN - poster
por: Hoorani, Hafeez, et al.
Publicado: (2014)

Impact of ABCB1 Polymorphism on Levetiracetam Serum Concentrations in Epileptic Uygur Children in China
por: Zhao, Ting, et al.
Publicado: (2020)

Association of ABCB1 Polymorphisms with Efficacy and Adverse Drug Reactions of Valproic Acid in Children with Epilepsy
por: Zhu, Jiahao, et al.
Publicado: (2023)

Genetic Polymorphisms Affecting Tacrolimus Metabolism and the Relationship to Post-Transplant Outcomes in Kidney Transplant Recipients
por: Cheng, Fang, et al.
Publicado: (2021)

The Impact of Single Nucleotide Polymorphisms on the Pharmacokinetics of Tacrolimus in Kidney Allograft Recipients of Northern-West, Iran
por: Jabbari Hagh, Elaheh, et al.
Publicado: (2023)

Tacrolimus trough levels in kidney transplant recipients
por: Hwang, Young Hui, et al.
Publicado: (2021)

Effect of CYP3 A4, CYP3 A5 and ABCB1 gene polymorphisms on the clinical efficacy of tacrolimus in the treatment of nephrotic syndrome
por: Li, Min, et al.
Publicado: (2018)

The Tacrolimus Concentration/Dose Ratio Does Not Predict Early Complications After Kidney Transplantation
por: von Samson-Himmelstjerna, Friedrich Alexander, et al.
Publicado: (2023)

The influence of recipient SLCO1B1 rs2291075 polymorphism on tacrolimus dose–corrected trough concentration in the early period after liver transplantation
por: Wu, Yi, et al.
Publicado: (2021)

Impact of ABCB1 Polymorphisms on Lacosamide Serum Concentrations in Uygur Pediatric Patients With Epilepsy in China
por: Zhao, Ting, et al.
Publicado: (2022)

Association between medication adherence and intrapatient variability in tacrolimus concentration among stable kidney transplant recipients
por: Ko, Hyunmin, et al.
Publicado: (2021)

CYP3A-status is associated with blood concentration and dose-requirement of tacrolimus in heart transplant recipients
por: Déri, Máté, et al.
Publicado: (2021)

Polymorphisms in MTHFR, MS and CBS Genes and Homocysteine Levels in a Pakistani Population
por: Yakub, Mohsin, et al.
Publicado: (2012)

A Randomized Pharmacokinetic Study of Generic Tacrolimus Versus Reference Tacrolimus in Kidney Transplant Recipients
por: Alloway, R R, et al.
Publicado: (2012)

Effect of cytochrome P450 3A5 polymorphism on the pharmacokinetics of tacrolimus in renal transplant recipients
por: Htun, Yi Yi, et al.
Publicado: (2020)

Why dose adjust systemic exposure when looking for associations with adverse events in tacrolimus‐treated transplant recipients?
por: Robertsen, Ida, et al.
Publicado: (2019)

ABCB1 1199G>A Genetic Polymorphism (Rs2229109) Influences the Intracellular Accumulation of Tacrolimus in HEK293 and K562 Recombinant Cell Lines
por: Dessilly, Géraldine, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_n18lt8kfms10uiif6es7bs352i