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Latent TGF-β Activation Is a Hallmark of the Tenascin Family
Transforming growth factor-β (TGF-β) isoforms are secreted as inactive complexes formed through non-covalent interactions between bioactive TGF-β entities and their N-terminal pro-domains called latency-associated peptides (LAP). Extracellular activation of latent TGF-β within this complex is a cruc...
Autores principales: | Aubert, Alexandre, Mercier-Gouy, Perrine, Aguero, Stéphanie, Berthier, Laurent, Liot, Sophie, Prigent, Laura, Alcaraz, Lindsay B., Verrier, Bernard, Terreux, Raphaël, Moali, Catherine, Lambert, Elise, Valcourt, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155481/ https://www.ncbi.nlm.nih.gov/pubmed/34054795 http://dx.doi.org/10.3389/fimmu.2021.613438 |
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