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DNA Topoisomerase 3α Is Involved in Homologous Recombination Repair and Replication Stress Response in Trypanosoma cruzi

DNA topoisomerases are enzymes that modulate DNA topology. Among them, topoisomerase 3α is engaged in genomic maintenance acting in DNA replication termination, sister chromatid separation, and dissolution of recombination intermediates. To evaluate the role of this enzyme in Trypanosoma cruzi, the...

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Detalles Bibliográficos
Autores principales: Costa-Silva, Héllida Marina, Resende, Bruno Carvalho, Umaki, Adriana Castilhos Souza, Prado, Willian, da Silva, Marcelo Santos, Virgílio, Stela, Macedo, Andrea Mara, Pena, Sérgio Danilo Junho, Tahara, Erich Birelli, Tosi, Luiz Ricardo Orsini, Elias, Maria Carolina, Andrade, Luciana Oliveira, Reis-Cunha, João Luís, Franco, Glória Regina, Fragoso, Stenio Perdigão, Machado, Carlos Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155511/
https://www.ncbi.nlm.nih.gov/pubmed/34055812
http://dx.doi.org/10.3389/fcell.2021.633195