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DNA Topoisomerase 3α Is Involved in Homologous Recombination Repair and Replication Stress Response in Trypanosoma cruzi
DNA topoisomerases are enzymes that modulate DNA topology. Among them, topoisomerase 3α is engaged in genomic maintenance acting in DNA replication termination, sister chromatid separation, and dissolution of recombination intermediates. To evaluate the role of this enzyme in Trypanosoma cruzi, the...
Autores principales: | Costa-Silva, Héllida Marina, Resende, Bruno Carvalho, Umaki, Adriana Castilhos Souza, Prado, Willian, da Silva, Marcelo Santos, Virgílio, Stela, Macedo, Andrea Mara, Pena, Sérgio Danilo Junho, Tahara, Erich Birelli, Tosi, Luiz Ricardo Orsini, Elias, Maria Carolina, Andrade, Luciana Oliveira, Reis-Cunha, João Luís, Franco, Glória Regina, Fragoso, Stenio Perdigão, Machado, Carlos Renato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155511/ https://www.ncbi.nlm.nih.gov/pubmed/34055812 http://dx.doi.org/10.3389/fcell.2021.633195 |
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