TRIM71 Deficiency Causes Germ Cell Loss During Mouse Embryogenesis and Is Associated With Human Male Infertility

Mutations affecting the germline can result in infertility or the generation of germ cell tumors (GCT), highlighting the need to identify and characterize the genes controlling germ cell development. The RNA-binding protein and E3 ubiquitin ligase TRIM71 is essential for embryogenesis, and its expre...

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Detalles Bibliográficos
Autores principales: Torres-Fernández, Lucia A., Emich, Jana, Port, Yasmine, Mitschka, Sibylle, Wöste, Marius, Schneider, Simon, Fietz, Daniela, Oud, Manon S., Di Persio, Sara, Neuhaus, Nina, Kliesch, Sabine, Hölzel, Michael, Schorle, Hubert, Friedrich, Corinna, Tüttelmann, Frank, Kolanus, Waldemar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155544/
https://www.ncbi.nlm.nih.gov/pubmed/34055789
http://dx.doi.org/10.3389/fcell.2021.658966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155544/
https://www.ncbi.nlm.nih.gov/pubmed/34055789
http://dx.doi.org/10.3389/fcell.2021.658966

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