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Renoprotective Effect of the Recombinant Anti-IL-6R Fusion Proteins by Inhibiting JAK2/STAT3 Signaling Pathway in Diabetic Nephropathy

Diabetic nephropathy the main reason for end stage renal disease is a common microvascular complication in patients with type 1 and type 2 diabetes. The interleukin-6 (IL-6), acting as a pleiotropic cytokine, play key roles in main autoimmune disorders. The recombinant anti-IL-6R fusion proteins (VH...

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Detalles Bibliográficos
Autores principales:	Zhang, Nanwen, Zheng, Qingmei, Wang, Yaduan, Lin, Juan, Wang, He, Liu, Rui, Yan, Mengru, Chen, Xiaofeng, Yang, Juhua, Chen, Xiaole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155588/ https://www.ncbi.nlm.nih.gov/pubmed/34054555 http://dx.doi.org/10.3389/fphar.2021.681424

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